Literature DB >> 202651

The genetic mapping of a defective LPS response gene in C3H/HeJ mice.

J Watson, K Kelly, M Largen, B A Taylor.   

Abstract

The expression of a defective LPS response gene Lps and the major urinary protein (Mup-1) are concordantly inherited in backcross (C3H/HeJ x C57BL/6J)F1 x C3H/HeJ mice, indicating genetic linkage of these loci. Mup-1 is known to be linked to the brown coat color locus on chromosome 4 in mice; thus Lps can now be assigned to chromosome 4. A value of 0.06 +/- 0.02 has been estimated for the recombination frequency between Mup-1 and Lps. We have used the polysyndactyly (Ps) mutation further to localize Lps on chromosome 4. Lps is located between the Mup-1 and Ps loci.

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Year:  1978        PMID： 202651

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  59 in total

1.  Dominant negative down-regulation of endotoxin-induced tumor necrosis factor alpha production by Lps(d)/Ran.

Authors:  Q Yuan; F Zhao; S W Chung; P Fan; B M Sultzer; Y W Kan; P M Wong
Journal:  Proc Natl Acad Sci U S A       Date:  2000-03-14       Impact factor: 11.205

2.  The role of Kupffer cell activation and viral gene expression in early liver toxicity after infusion of recombinant adenovirus vectors.

Authors:  A Lieber; C Y He; L Meuse; D Schowalter; I Kirillova; B Winther; M A Kay
Journal:  J Virol       Date:  1997-11       Impact factor: 5.103

Review 3.  Mouse chromosome 4.

Authors:  R Blank; J Eppig; F T Fiedorek; W N Frankel; J M Friedman; K Huppi; I Jackson; B Mock
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

4.  Genetic basis for unresponsiveness to lipopolysaccharide in C57BL/10Cr mice.

Authors:  A Coutinho; T Meo
Journal:  Immunogenetics       Date:  1978-12       Impact factor: 2.846

5.  Role of macrophages in regeneration of liver.

Authors:  Y Shiratori; S Hongo; Y Hikiba; K Ohmura; T Nagura; K Okano; K Kamii; T Tanaka; Y Komatsu; T Ochiai; H Tsubouchi; M Omata
Journal:  Dig Dis Sci       Date:  1996-10       Impact factor: 3.199

6.  Dissociation of innate susceptibility to Salmonella infection and endotoxin responsiveness in C3HeB/FeJ mice and other strains in the C3H lineage.

Authors:  T K Eisenstein; L W Deakins; L Killar; P H Saluk; B M Sultzer
Journal:  Infect Immun       Date:  1982-05       Impact factor: 3.441

Review 7.  Genetics-squared: combining host and pathogen genetics in the analysis of innate immunity and bacterial virulence.

Authors:  Jenny Persson; Russell E Vance
Journal:  Immunogenetics       Date:  2007-09-14       Impact factor: 2.846

8.  Spacious phagosome formation within mouse macrophages correlates with Salmonella serotype pathogenicity and host susceptibility.

Authors:  C M Alpuche-Aranda; E P Berthiaume; B Mock; J A Swanson; S I Miller
Journal:  Infect Immun       Date:  1995-11       Impact factor: 3.441

9.  Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningococcal susceptibility.

Authors:  Irina Smirnova; Navjiwan Mann; Annemiek Dols; H H Derkx; Martin L Hibberd; Michael Levin; Bruce Beutler
Journal:  Proc Natl Acad Sci U S A       Date:  2003-05-02       Impact factor: 11.205

10.  Bacterial virulence versus host resistance in the urinary tracts of mice.

Authors:  C Svanborg-Edén; L Hagberg; R Hull; S Hull; K E Magnusson; L Ohman
Journal:  Infect Immun       Date:  1987-05       Impact factor: 3.441
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