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Literature DB >> 7927341

Parental origin of the extra chromosomes in polysomy X.

C A Leal¹, J W Belmont, R Nachtman, J M Cantu, C Medina.

Abstract

Five polymorphic index markers were analyzed by polymerase chain reaction (PCR) to ascertain the parental origin of the extra X chromosomes in seven polysomic cases (one 49,XXXXX, three 49,XXXXY, two 48,XXXY, and one 48,XXYY). All four X chromosomes in 49, X polysomies were maternal in origin and the extra X chromosomes in 48 X polysomies were paternal. In each case the multiple X chromosomes were contributed by a single parent. Taken together with previously reported cases, these data support a single mechanism of sequential nondisjunction during either maternal or paternal gametogenesis as the cause of higher order sex chromosome polysomy.

Mesh：

Substances：
DNA

Year: 1994 PMID： 7927341 DOI： 10.1007/bf00201605

Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132

20 in total

1. Determination of the origin of nondisjunction in a 49,XXXXY male using hypervariable dinucleotide repeat sequences.

Authors: T H Huang; F Greenberg; D H Ledbetter
Journal: Hum Genet Date: 1991-04 Impact factor: 4.132

2. Analysis of non-disjunction in sex chromosome tetrasomy and pentasomy.

Authors: T Hassold; D Pettay; K May; A Robinson
Journal: Hum Genet Date: 1990-10 Impact factor: 4.132

3. Origin of the X chromosomes in a patient with the 49,XXXXY syndrome.

Authors: D S Plaha; D P Duckett; R A Collacott; I D Young
Journal: J Med Genet Date: 1990-03 Impact factor: 6.318

4. A simple salting out procedure for extracting DNA from human nucleated cells.

Authors: S A Miller; D D Dykes; H F Polesky
Journal: Nucleic Acids Res Date: 1988-02-11 Impact factor: 16.971

5. The parental origin of the extra X chromosome in 47,XXX females.

Authors: K M May; P A Jacobs; M Lee; S Ratcliffe; A Robinson; J Nielsen; T J Hassold
Journal: Am J Hum Genet Date: 1990-04 Impact factor: 11.025

6. Parental origin of chromosomal nondisjunction in a 49,XXXXY male using recombinant-DNA techniques.

Authors: M Villamar; J Benitez; E Fernández; C Ayuso; C Ramos
Journal: Clin Genet Date: 1989-09 Impact factor: 4.438

7. Origin of 48,XXXY: the evidence of the Xg blood groups.

Authors: R A Pfeiffer; R Sanger
Journal: J Med Genet Date: 1973-06 Impact factor: 6.318

8. Xg groups and sex abnormalities in people of northern European ancestry.

Authors: R Sanger; P Tippett; J Gavin
Journal: J Med Genet Date: 1971-12 Impact factor: 6.318

9. Dinucleotide repeat polymorphism in the human CD40 ligand gene.

Authors: R C Allen; M K Spriggs; J W Belmont
Journal: Hum Mol Genet Date: 1993-06 Impact factor: 6.150

10. X-chromosome polysomy in the male. The Leuven experience 1966-1987.

Authors: A Kleczkowska; J P Fryns; H Van den Berghe
Journal: Hum Genet Date: 1988-09 Impact factor: 4.132

8 in total

Review 1. 48,XXYY, 48,XXXY and 49,XXXXY syndromes: not just variants of Klinefelter syndrome.

Authors: Nicole Tartaglia; Natalie Ayari; Susan Howell; Cheryl D'Epagnier; Philip Zeitler
Journal: Acta Paediatr Date: 2011-04-08 Impact factor: 2.299

2. Double non-disjunction in maternal meiosis II giving rise to a fetus with 48,XXX,+21.

Authors: V M Park; R R Bravo; L P Shulman
Journal: J Med Genet Date: 1995-08 Impact factor: 6.318

3. 49,XXXXY: a distinct phenotype. Three new cases and review.

Authors: J Peet; D D Weaver; G H Vance
Journal: J Med Genet Date: 1998-05 Impact factor: 6.318

4. A new look at XXYY syndrome: medical and psychological features.

Authors: Nicole Tartaglia; Shanlee Davis; Alison Hench; Sheela Nimishakavi; Renee Beauregard; Ann Reynolds; Laura Fenton; Lindsey Albrecht; Judith Ross; Jeannie Visootsak; Robin Hansen; Randi Hagerman
Journal: Am J Med Genet A Date: 2008-06-15 Impact factor: 2.802