Literature DB >> 7922876

The development and applications of sucralose, a new high-intensity sweetener.

I Knight1.   

Abstract

Sucralose is a new sweetener discovered during a collaborative research program between Tate & Lyle and Queen Elizabeth College of the University of London. It is made by selective substitution of sucrose hydroxyl groups by chlorine, resulting in a highly intense (600x) sugarlike sweetness and exceptional stability at both high temperature and low pH. The research leading to the discovery of sweetness in differently halogenated sucrose is described, as well as the development of sucralose and the process of safety testing and government approval. Finally, sucralose properties and applications in Canada's food and beverage industries are discussed.

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Year:  1994        PMID: 7922876     DOI: 10.1139/y94-063

Source DB:  PubMed          Journal:  Can J Physiol Pharmacol        ISSN: 0008-4212            Impact factor:   2.273


  19 in total

Review 1.  Pharmacological approaches for the treatment of obesity.

Authors:  José-Antonio Fernández-López; Xavier Remesar; Màrius Foz; Marià Alemany
Journal:  Drugs       Date:  2002       Impact factor: 9.546

2.  What made Canada become a country with the highest incidence of inflammatory bowel disease: could sucralose be the culprit?

Authors:  Xiaofa Qin
Journal:  Can J Gastroenterol       Date:  2011-09       Impact factor: 3.522

3.  Development of high protein, high fiber smoothie as a grab-and-go breakfast option using response surface methodology.

Authors:  Dipakkumar Mehta; M H Sathish Kumar; Latha Sabikhi
Journal:  J Food Sci Technol       Date:  2017-09-11       Impact factor: 2.701

4.  Rats display a robust bimodal preference profile for sucralose.

Authors:  Gregory C Loney; Ann-Marie Torregrossa; James C Smith; Anthony Sclafani; Lisa A Eckel
Journal:  Chem Senses       Date:  2011-06-08       Impact factor: 3.160

5.  Neuroprotective efficacy of lifarizine (RS-87476) in a simplified rat survival model of 2 vessel occlusion.

Authors:  D E McBean; V Winters; A D Wilson; C B Oswald; B J Alps; J M Armstrong
Journal:  Br J Pharmacol       Date:  1995-12       Impact factor: 8.739

Review 6.  Etiology of inflammatory bowel disease: a unified hypothesis.

Authors:  Xiaofa Qin
Journal:  World J Gastroenterol       Date:  2012-04-21       Impact factor: 5.742

Review 7.  Intestinal permeability, leaky gut, and intestinal disorders.

Authors:  D Hollander
Journal:  Curr Gastroenterol Rep       Date:  1999-10

8.  Actions of the novel neuroprotective agent, lifarizine (RS-87476), on voltage-dependent sodium currents in the neuroblastoma cell line, N1E-115.

Authors:  J G McGivern; L Patmore; R D Sheridan
Journal:  Br J Pharmacol       Date:  1995-04       Impact factor: 8.739

9.  Altered sensitization patterns to sweet food stimuli in patients recovered from anorexia and bulimia nervosa.

Authors:  Angela Wagner; Alan N Simmons; Tyson A Oberndorfer; Guido K W Frank; Danyale McCurdy-McKinnon; Julie L Fudge; Tony T Yang; Martin P Paulus; Walter H Kaye
Journal:  Psychiatry Res       Date:  2015-11-10       Impact factor: 3.222

Review 10.  Artificial sweeteners - a review.

Authors:  Sanchari Chattopadhyay; Utpal Raychaudhuri; Runu Chakraborty
Journal:  J Food Sci Technol       Date:  2011-10-21       Impact factor: 2.701

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