Literature DB >> 7920429

Anti-inflammatory constituents of topically applied crude drugs. V. Constituents and anti-inflammatory effect of Aoki, Aucuba japonica Thunb.

M Shimizu1, T Tomoo.   

Abstract

The Et2O-soluble fraction of the MeOH extract of the leaves of Aucuba japonica Thunb. showed an anti-inflammatory effect when topically applied to rats. E-Phytol, phytone, bis(2-ethylhexyl)phthalate and friedelin were isolated as active anti-inflammatory components inhibiting carrageenin-induced paw edema. The most effective, E-phytol, inhibited histamine-induced paw edema more potently than the compound 48/80-induced edema, suggesting that the mechanism of action is due to inhibition of the H1 receptor.

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Year:  1994        PMID： 7920429     DOI： 10.1248/bpb.17.665

Source DB:  PubMed          Journal:  Biol Pharm Bull        ISSN： 0918-6158            Impact factor:   2.233


  10 in total

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Authors:  Brett J West; Shixin Deng; Afa K Palu; C Jarakae Jensen
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3.  Brown Pine Leaf Extract and Its Active Component Trans-Communic Acid Inhibit UVB-Induced MMP-1 Expression by Targeting PI3K.

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Journal:  PLoS One       Date:  2015-06-11       Impact factor: 3.240

Review 4.  Uncovering Potential Applications of Cyanobacteria and Algal Metabolites in Biology, Agriculture and Medicine: Current Status and Future Prospects.

Authors:  Rachana Singh; Parul Parihar; Madhulika Singh; Andrzej Bajguz; Jitendra Kumar; Samiksha Singh; Vijay P Singh; Sheo M Prasad
Journal:  Front Microbiol       Date:  2017-04-25       Impact factor: 5.640

5.  In Vitro Wound Healing Potential of Stem Extract of Alternanthera sessilis.

Authors:  Katyakyini Muniandy; Sivapragasam Gothai; Woan Sean Tan; S Suresh Kumar; Norhaizan Mohd Esa; Govindasamy Chandramohan; Khalid S Al-Numair; Palanisamy Arulselvan
Journal:  Evid Based Complement Alternat Med       Date:  2018-02-19       Impact factor: 2.629

6.  Phytol is a novel tumor promoter on ICR mouse skin.

Authors:  M Kagoura; C Matsui; M Morohashi
Journal:  Jpn J Cancer Res       Date:  1999-04

7.  In vitro inhibitory effects of Friedelin on human liver cytochrome P450 enzymes.

Authors:  Jinlan Wei; Hongying Zhang; Qingling Zhao
Journal:  Pharm Biol       Date:  2018-12       Impact factor: 3.503

8.  Crude leaf extracts of Piperaceae species downmodulate inflammatory responses by human monocytes.

Authors:  Angela Carolina Finato; Thais Fernanda Fraga-Silva; Amanda Uliana Carvalho Prati; Amauri Alves de Souza Júnior; Bruna Fonseca Mazzeu; Lidiane Gaspareto Felippe; Rute Alves Pinto; Marjorie de Assis Golim; Maria Sueli Parreira Arruda; Maysa Furlan; James Venturini
Journal:  PLoS One       Date:  2018-06-20       Impact factor: 3.240

9.  Aucubin, An Active Ingredient in Aucuba japonica, Prevents N-methyl-N-nitrosourea-induced Retinal Degeneration in Mice.

Authors:  Eunsoo Jung; Su-Bin Park; Woo Kwon Jung; Hyung Rae Kim; Junghyun Kim
Journal:  Molecules       Date:  2019-12-04       Impact factor: 4.411

10.  Phytol-based novel adjuvants in vaccine formulation: 1. assessment of safety and efficacy during stimulation of humoral and cell-mediated immune responses.

Authors:  So-Yon Lim; Matt Meyer; Richard A Kjonaas; Swapan K Ghosh
Journal:  J Immune Based Ther Vaccines       Date:  2006-10-30
  10 in total

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