Literature DB >> 7918702

Decreased benzodiazepine receptor binding in panic disorder measured by IOMAZENIL-SPECT. A preliminary report.

S Schlegel1, H Steinert, A Bockisch, K Hahn, R Schloesser, O Benkert.   

Abstract

Single photon emission tomography (SPECT) imaging of the central benzodiazepine receptor (BZr) became possible with the newly developed ligand 123I-IOMAZENIL. The BZr binding was investigated in ten patients with panic disorder (PP) compared to ten epileptic patients (EP). Panic patients had lower IOMAZENIL uptake rates in the frontal, occipital and temporal cortex than EP indicating the involvement of the BZr complex in panic disorder.

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Year:  1994        PMID： 7918702     DOI： 10.1007/bf02279812

Source DB:  PubMed          Journal:  Eur Arch Psychiatry Clin Neurosci        ISSN： 0940-1334            Impact factor:   5.270


  16 in total

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Authors:  A Breier; S M Paul
Journal:  J Psychiatr Res       Date:  1990       Impact factor: 4.791

2.  In-vivo demonstration of reduced benzodiazepine receptor binding in human epileptic foci.

Authors:  I Savic; A Persson; P Roland; S Pauli; G Sedvall; L Widén
Journal:  Lancet       Date:  1988-10-15       Impact factor: 79.321

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Authors:  T R Norman; G D Burrows
Journal:  Prog Brain Res       Date:  1986       Impact factor: 2.453

4.  Differences in benzodiazepine receptor binding in Maudsley reactive and Maudsley non-reactive rats.

Authors:  H A Robertson; I L Martin; J M Candy
Journal:  Eur J Pharmacol       Date:  1978-08-15       Impact factor: 4.432

5.  Reduced benzodiazepine sensitivity in panic disorder.

Authors:  P P Roy-Byrne; D S Cowley; D J Greenblatt; R I Shader; D Hommer
Journal:  Arch Gen Psychiatry       Date:  1990-06

6.  Repeated swim stress alters brain benzodiazepine receptors measured in vivo.

Authors:  R Weizman; A Weizman; K A Kook; F Vocci; S I Deutsch; S M Paul
Journal:  J Pharmacol Exp Ther       Date:  1989-06       Impact factor: 4.030

7.  Changes in benzodiazepine receptors by acute stress: different effect of chronic diazepam or RO 15-1788 treatment.

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Journal:  Eur J Pharmacol       Date:  1983-12-23       Impact factor: 4.432

8.  Dosimetry of iodine-123 iomazenil in humans.

Authors:  N P Verhoeff; E Busemann Sokole; D Hengst; J B Stubbs; E A van Royen
Journal:  Eur J Nucl Med       Date:  1993-07

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Journal:  J Pharmacol Exp Ther       Date:  1988-07       Impact factor: 4.030

Review 10.  The neurochemistry of anxiety: an update.

Authors:  D J Nutt; P Glue; C Lawson
Journal:  Prog Neuropsychopharmacol Biol Psychiatry       Date:  1990       Impact factor: 5.067
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  13 in total

Review 1.  Revise the revised? New dimensions of the neuroanatomical hypothesis of panic disorder.

Authors:  Thomas Dresler; Anne Guhn; Sara V Tupak; Ann-Christine Ehlis; Martin J Herrmann; Andreas J Fallgatter; Jürgen Deckert; Katharina Domschke
Journal:  J Neural Transm (Vienna)       Date:  2012-06-13       Impact factor: 3.575

2.  Acute pharmacological modulation of mGluR8 reduces measures of anxiety.

Authors:  Robert M Duvoisin; Tim Pfankuch; Julie M Wilson; Julie Grabell; Vijay Chhajlani; Dean G Brown; Edwin Johnson; Jacob Raber
Journal:  Behav Brain Res       Date:  2010-04-10       Impact factor: 3.332

Review 3.  Molecular pathways of anxiety revealed by knockout mice.

Authors:  S J Wood; M Toth
Journal:  Mol Neurobiol       Date:  2001 Apr-Jun       Impact factor: 5.590

4.  Opposing roles of mGluR8 in measures of anxiety involving non-social and social challenges.

Authors:  Robert M Duvoisin; Laura Villasana; Matthew J Davis; Danny G Winder; Jacob Raber
Journal:  Behav Brain Res       Date:  2011-03-04       Impact factor: 3.332

5.  Genetic inactivation of the Serotonin(1A) receptor in mice results in downregulation of major GABA(A) receptor alpha subunits, reduction of GABA(A) receptor binding, and benzodiazepine-resistant anxiety.

Authors:  E Sibille; C Pavlides; D Benke; M Toth
Journal:  J Neurosci       Date:  2000-04-15       Impact factor: 6.167

6.  Delayed image of iodine-123 iomazenil as a relative map of benzodiazepine receptor binding: the optimal scan time.

Authors:  Y Onishi; Y Yonekura; F Tanaka; S Nishizawa; H Okazawa; K Ishizu; T Fujita; J Konishi; T Mukai
Journal:  Eur J Nucl Med       Date:  1996-11

7.  Carbon-11 and iodine-123 labelled iomazenil: a direct PET-SPET compari son.

Authors:  G Westera; A Buck; C Burger; K L Leenders; G K von Schulthess; A P Schubiger
Journal:  Eur J Nucl Med       Date:  1996-01

8.  GABAA-benzodiazepine receptor availability in smokers and nonsmokers: relationship to subsyndromal anxiety and depression.

Authors:  Irina Esterlis; Kelly P Cosgrove; Jeffery C Batis; Frederic Bois; Tracy A Kloczynski; Stephanie M Stiklus; Edward Perry; Gilles D Tamagnan; John P Seibyl; Robert Makuch; Suchitra Krishnan-Sarin; Stephanie O'Malley; Julie K Staley
Journal:  Synapse       Date:  2009-12       Impact factor: 2.562

9.  Decreased GABA levels in anterior cingulate cortex/medial prefrontal cortex in panic disorder.

Authors:  Zaiyang Long; Carla Medlock; Mario Dzemidzic; Yong-Wook Shin; Andrew W Goddard; Ulrike Dydak
Journal:  Prog Neuropsychopharmacol Biol Psychiatry       Date:  2013-02-04       Impact factor: 5.067

10.  Cortical thinning in obsessive compulsive disorder.

Authors:  Yong-Wook Shin; So Young Yoo; Jun Ki Lee; Tae Hyon Ha; Kyung Jin Lee; Jong Min Lee; In Young Kim; Sun I Kim; Jun Soo Kwon
Journal:  Hum Brain Mapp       Date:  2007-11       Impact factor: 5.038
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