| Literature DB >> 7916157 |
P Bollini1, S Pampallona, M J Orza, M E Adams, T C Chalmers.
Abstract
Effectiveness and side-effects of high- versus low-dose neuroleptic treatment of chronic psychosis have been assessed through a meta-analysis of 22 published randomized control trials comparing different neuroleptic doses. No incremental clinical improvement was found at doses above 375 mg equivalent of chlorpromazine, while a significant increase in adverse reactions was observed.Entities:
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Year: 1994 PMID： 7916157 DOI： 10.1017/s003329170002729x
Source DB: PubMed Journal: Psychol Med ISSN： 0033-2917 Impact factor: 7.723