Literature DB >> 7911266

Clinical evaluation of sizofilan as assistant immunotherapy in treatment of head and neck cancer.

Y Kimura1, H Tojima, S Fukase, K Takeda.   

Abstract

Sizofilan (SPG), a simple glucan produced in a culture medium by Schizophyllum commune Feries, was used as an assistant immunotherapy in 15 patients with head and neck cancer. The cumulative 5-year survival rate was 86.7% in the SPG-treated group and 73.4% in the control group. Immunological parameters showed that the SPG group quickly recovered the cellular immunity damaged by radiation, chemotherapy and surgical procedure. SPG was found to be effective as an assistant immunotherapeutic agent in the treatment of head and neck.

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Year:  1994        PMID： 7911266     DOI： 10.3109/00016489409128330

Source DB:  PubMed          Journal:  Acta Otolaryngol Suppl        ISSN： 0365-5237


  7 in total

1.  Glucan-immunostimulant, adjuvant, potential drug.

Authors:  Vaclav Vetvicka
Journal:  World J Clin Oncol       Date:  2011-02-10

2.  Schizophyllan inhibits the development of mammary and hepatic carcinomas induced by 7,12 dimethylbenz(α)anthracene and decreases cell proliferation: comparison with tamoxifen.

Authors:  Ahmed Mansour; Ayman Daba; Nahed Baddour; Muhammed El-Saadani; Eiman Aleem
Journal:  J Cancer Res Clin Oncol       Date:  2012-05-03       Impact factor: 4.553

Review 3.  Mushroom Polysaccharide-Assisted Anticarcinogenic Mycotherapy: Reviewing Its Clinical Trials.

Authors:  Iyyakkannu Sivanesan; Manikandan Muthu; Judy Gopal; Jae-Wook Oh
Journal:  Molecules       Date:  2022-06-25       Impact factor: 4.927

Review 4.  Recent progress in fungus-derived bioactive agents for targeting of signaling machinery in cancer cells.

Authors:  Xiukun Lin; Ammad Ahmad Farooqi; Muhammad Ismail
Journal:  Drug Des Devel Ther       Date:  2015-03-26       Impact factor: 4.162

5.  High- and low-Molecular Weight oat Beta-Glucan Reveals Antitumor Activity in Human Epithelial Lung Cancer.

Authors:  Anna Choromanska; Julita Kulbacka; Joanna Harasym; Remigiusz Oledzki; Anna Szewczyk; Jolanta Saczko
Journal:  Pathol Oncol Res       Date:  2017-07-29       Impact factor: 3.201

Review 6.  Mycobiota and C-Type Lectin Receptors in Cancers: Know thy Neighbors.

Authors:  Lilong Zhang; Dongqi Chai; Chen Chen; Chunlei Li; Zhendong Qiu; Tianrui Kuang; Mungur Parveena; Keshuai Dong; Jia Yu; Wenhong Deng; Weixing Wang
Journal:  Front Microbiol       Date:  2022-07-13       Impact factor: 6.064

7.  Oral treatment with T6-loaded yeast cell wall particles reduces the parasitemia in murine visceral leishmaniasis model.

Authors:  Débora B Scariot; Hélito Volpato; Nilma S Fernandes; Danielle Lazarin-Bidóia; Olga Borges; Maria do Céu Sousa; Fernanda A Rosa; Andrey P Jacomini; Sueli O Silva; Tânia Ueda-Nakamura; Adley F Rubira; Celso V Nakamura
Journal:  Sci Rep       Date:  2019-12-27       Impact factor: 4.379
  7 in total

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