Literature DB >> 7889326

Efflux pumps and drug resistance in gram-negative bacteria.

D Ma1, D N Cook, J E Hearst, H Nikaido.   

Abstract

The outer membrane of Gram-negative bacteria can only slow down the influx of lipophilic inhibitors, and so these bacteria need active efflux pumps of broad specificity to survive. Pumps such as the Escherichia coli Acr system and its homologs make Gram-negative bacteria resistant to dyes, detergents and antibiotics.

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Year:  1994        PMID: 7889326     DOI: 10.1016/0966-842x(94)90654-8

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN: 0966-842X            Impact factor:   17.079


  104 in total

1.  Antibiotic susceptibility profiles of Escherichia coli strains lacking multidrug efflux pump genes.

Authors:  M C Sulavik; C Houseweart; C Cramer; N Jiwani; N Murgolo; J Greene; B DiDomenico; K J Shaw; G H Miller; R Hare; G Shimer
Journal:  Antimicrob Agents Chemother       Date:  2001-04       Impact factor: 5.191

2.  AcrD of Escherichia coli is an aminoglycoside efflux pump.

Authors:  E Y Rosenberg; D Ma; H Nikaido
Journal:  J Bacteriol       Date:  2000-03       Impact factor: 3.490

3.  Insertion mutagenesis and membrane topology model of the Pseudomonas aeruginosa outer membrane protein OprM.

Authors:  K K Wong; R E Hancock
Journal:  J Bacteriol       Date:  2000-05       Impact factor: 3.490

Review 4.  Molecular properties of bacterial multidrug transporters.

Authors:  M Putman; H W van Veen; W N Konings
Journal:  Microbiol Mol Biol Rev       Date:  2000-12       Impact factor: 11.056

5.  Carboxy-terminal region involved in activity of Escherichia coli TolC.

Authors:  H Yamanaka; H Izawa; K Okamoto
Journal:  J Bacteriol       Date:  2001-12       Impact factor: 3.490

6.  Three efflux pumps are required to provide efficient tolerance to toluene in Pseudomonas putida DOT-T1E.

Authors:  A Rojas; E Duque; G Mosqueda; G Golden; A Hurtado; J L Ramos; A Segura
Journal:  J Bacteriol       Date:  2001-07       Impact factor: 3.490

Review 7.  Efflux-mediated resistance to fluoroquinolones in gram-negative bacteria.

Authors:  K Poole
Journal:  Antimicrob Agents Chemother       Date:  2000-09       Impact factor: 5.191

8.  Suppression of hypersensitivity of Escherichia coli acrB mutant to organic solvents by integrational activation of the acrEF operon with the IS1 or IS2 element.

Authors:  K Kobayashi; N Tsukagoshi; R Aono
Journal:  J Bacteriol       Date:  2001-04       Impact factor: 3.490

9.  Multidrug efflux pumps: expression patterns and contribution to antibiotic resistance in Pseudomonas aeruginosa biofilms.

Authors:  T R De Kievit; M D Parkins; R J Gillis; R Srikumar; H Ceri; K Poole; B H Iglewski; D G Storey
Journal:  Antimicrob Agents Chemother       Date:  2001-06       Impact factor: 5.191

10.  Contribution of resistance-nodulation-division efflux pump operon smeU1-V-W-U2-X to multidrug resistance of Stenotrophomonas maltophilia.

Authors:  Chao-Hsien Chen; Chiang-Ching Huang; Tsao-Chuen Chung; Rouh-Mei Hu; Yi-Wei Huang; Tsuey-Ching Yang
Journal:  Antimicrob Agents Chemother       Date:  2011-09-19       Impact factor: 5.191

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