Literature DB >> 7884923

DNA immunization confers protection against lethal lymphocytic choriomeningitis virus infection.

M Yokoyama1, J Zhang, J L Whitton.   

Abstract

DNA vaccination has been evaluated with the lymphocytic choriomeningitis virus (LCMV) model system. Plasmid DNA encoding the LCMV nucleoprotein, when injected intramuscularly, induces both antiviral antibodies and cytotoxic T lymphocytes. Injection of DNA encoding the nucleoprotein or the viral glycoprotein confers protection against normally lethal LCMV challenge in a major histocompatibility complex-dependent manner. The protection conferred is incomplete, but it is most probably mediated by the induced cytotoxic T lymphocytes.

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Year:  1995        PMID： 7884923      PMCID： PMC188955     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  28 in total

Review 1.  Arenavirus gene structure and organization.

Authors:  D H Bishop; D D Auperin
Journal:  Curr Top Microbiol Immunol       Date:  1987       Impact factor: 4.291

2.  Long-term anti-nucleoprotein cellular and humoral immunity is induced by intramuscular injection of plasmid DNA containing NP gene.

Authors:  M A Yankauckas; J E Morrow; S E Parker; A Abai; G H Rhodes; V J Dwarki; S H Gromkowski
Journal:  DNA Cell Biol       Date:  1993-11       Impact factor: 3.311

3.  Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice.

Authors:  D Kägi; B Ledermann; K Bürki; P Seiler; B Odermatt; K J Olsen; E R Podack; R M Zinkernagel; H Hengartner
Journal:  Nature       Date:  1994-05-05       Impact factor: 49.962

4.  Protection against a lethal influenza virus challenge by immunization with a haemagglutinin-expressing plasmid DNA.

Authors:  H L Robinson; L A Hunt; R G Webster
Journal:  Vaccine       Date:  1993       Impact factor: 3.641

5.  Protein structure of lymphocytic choriomeningitis virus: evidence for a cell-associated precursor of the virion glycopeptides.

Authors:  M J Buchmeier; M B Oldstone
Journal:  Virology       Date:  1979-11       Impact factor: 3.616

6.  Examination of parameters affecting the elicitation of humoral immune responses by particle bombardment-mediated genetic immunization.

Authors:  M D Eisenbraun; D H Fuller; J R Haynes
Journal:  DNA Cell Biol       Date:  1993-11       Impact factor: 3.311

7.  Immunity to MHC class I antigen after direct DNA transfer into skeletal muscle.

Authors:  E K Geissler; J Wang; J H Fechner; W J Burlingham; S J Knechtle
Journal:  J Immunol       Date:  1994-01-15       Impact factor: 5.422

8.  DNA-based immunization induces continuous secretion of hepatitis B surface antigen and high levels of circulating antibody.

Authors:  H L Davis; M L Michel; R G Whalen
Journal:  Hum Mol Genet       Date:  1993-11       Impact factor: 6.150

9.  DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations.

Authors:  E F Fynan; R G Webster; D H Fuller; J R Haynes; J C Santoro; H L Robinson
Journal:  Proc Natl Acad Sci U S A       Date:  1993-12-15       Impact factor: 11.205

10.  Vaccination with a plasmid vector carrying the rabies virus glycoprotein gene induces protective immunity against rabies virus.

Authors:  Z Q Xiang; S Spitalnik; M Tran; W H Wunner; J Cheng; H C Ertl
Journal:  Virology       Date:  1994-02-15       Impact factor: 3.616
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  50 in total

1.  Induction of antiviral antibodies by DNA immunization requires neither perforin-mediated nor CD8(+)-T-cell-mediated lysis of antigen-expressing cells.

Authors:  D E Hassett; J Zhang; J L Whitton
Journal:  J Virol       Date:  1999-09       Impact factor: 5.103

2.  Antiviral protection after DNA vaccination is short lived and not enhanced by CpG DNA.

Authors:  S Oehen; T Junt; C López-Macías; T A Kramps
Journal:  Immunology       Date:  2000-02       Impact factor: 7.397

3.  Immune responses following neonatal DNA vaccination are long-lived, abundant, and qualitatively similar to those induced by conventional immunization.

Authors:  D E Hassett; J Zhang; M Slifka; J L Whitton
Journal:  J Virol       Date:  2000-03       Impact factor: 5.103

4.  Intralymphatic immunization enhances DNA vaccination.

Authors:  K J Maloy; I Erdmann; V Basch; S Sierro; T A Kramps; R M Zinkernagel; S Oehen; T M Kündig
Journal:  Proc Natl Acad Sci U S A       Date:  2001-02-27       Impact factor: 11.205

5.  Delivery of multiple epitopes by recombinant detoxified adenylate cyclase of Bordetella pertussis induces protective antiviral immunity.

Authors:  C Fayolle; A Osickova; R Osicka; T Henry; M J Rojas; M F Saron; P Sebo; C Leclerc
Journal:  J Virol       Date:  2001-08       Impact factor: 5.103

6.  Neonates mount robust and protective adult-like CD8(+)-T-cell responses to DNA vaccines.

Authors:  Jie Zhang; Nicole Silvestri; J Lindsay Whitton; Daniel E Hassett
Journal:  J Virol       Date:  2002-12       Impact factor: 5.103

7.  Virus-induced diabetes in a transgenic model: role of cross-reacting viruses and quantitation of effector T cells needed to cause disease.

Authors:  N Sevilla; D Homann; M von Herrath; F Rodriguez; S Harkins; J L Whitton; M B Oldstone
Journal:  J Virol       Date:  2000-04       Impact factor: 5.103

8.  DNA immunization: ubiquitination of a viral protein enhances cytotoxic T-lymphocyte induction and antiviral protection but abrogates antibody induction.

Authors:  F Rodriguez; J Zhang; J L Whitton
Journal:  J Virol       Date:  1997-11       Impact factor: 5.103

9.  Immunization with non-replicating E. coli minicells delivering both protein antigen and DNA protects mice from lethal challenge with lymphocytic choriomeningitis virus.

Authors:  Matthew J Giacalone; Juan C Zapata; Neil L Berkley; Roger A Sabbadini; Yen-Lin Chu; Maria S Salvato; Kathleen L McGuire
Journal:  Vaccine       Date:  2006-12-26       Impact factor: 3.641

10.  Neonatal DNA immunization with a plasmid encoding an internal viral protein is effective in the presence of maternal antibodies and protects against subsequent viral challenge.

Authors:  D E Hassett; J Zhang; J L Whitton
Journal:  J Virol       Date:  1997-10       Impact factor: 5.103
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