Literature DB >> 7880382

The immunology of exceptional individuals: the lesson of centenarians.

C Franceschi1, D Monti, P Sansoni, A Cossarizza.   

Abstract

Centenarians are the best example of successful ageing, since they have escaped the major age-associated diseases, and most are in good mental and physical condition. Here, Claudio Franceschi and colleagues discuss how the study of their immune systems reveals that several immune parameters are well conserved, suggesting that a complex remodelling of most immune parameters occurs with age, rather than a unidirectional deterioration.

Mesh:

Year:  1995        PMID: 7880382     DOI: 10.1016/0167-5699(95)80064-6

Source DB:  PubMed          Journal:  Immunol Today        ISSN: 0167-5699


  76 in total

Review 1.  The immune system in the elderly: II. Specific cellular immunity.

Authors:  L Ginaldi; M De Martinis; A D'Ostilio; L Marini; M F Loreto; V Martorelli; D Quaglino
Journal:  Immunol Res       Date:  1999       Impact factor: 2.829

Review 2.  The immune system in the elderly: III. Innate immunity.

Authors:  L Ginaldi; M De Martinis; A D'Ostilio; L Marini; M F Loreto; D Quaglino
Journal:  Immunol Res       Date:  1999       Impact factor: 2.829

Review 3.  Age-related changes in immune function: effect on airway inflammation.

Authors:  Paula J Busse; Sameer K Mathur
Journal:  J Allergy Clin Immunol       Date:  2010-10       Impact factor: 10.793

Review 4.  The immune system in the elderly: activation-induced and damage-induced apoptosis.

Authors:  Lia Ginaldi; Massimo De Martinis; Daniela Monti; Claudio Franceschi
Journal:  Immunol Res       Date:  2004       Impact factor: 2.829

Review 5.  Successful ageing: from cell to self.

Authors:  S J Lupien; N Wan
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2004-09-29       Impact factor: 6.237

6.  Mechanistic insights into the impairment of memory B cells and antibody production in the elderly.

Authors:  Judith H Aberle; Karin Stiasny; Michael Kundi; Franz X Heinz
Journal:  Age (Dordr)       Date:  2012-01-27

Review 7.  The immune system in the aging human.

Authors:  Paulina Dominika Rymkiewicz; Yi Xiong Heng; Anusha Vasudev; Anis Larbi
Journal:  Immunol Res       Date:  2012-09       Impact factor: 2.829

Review 8.  Aging and immune function: molecular mechanisms to interventions.

Authors:  Subramaniam Ponnappan; Usha Ponnappan
Journal:  Antioxid Redox Signal       Date:  2011-01-08       Impact factor: 8.401

Review 9.  Impact of aging on dendritic cell functions in humans.

Authors:  Anshu Agrawal; Sudhir Gupta
Journal:  Ageing Res Rev       Date:  2010-07-07       Impact factor: 10.895

Review 10.  Age effects on B cells and humoral immunity in humans.

Authors:  Daniela Frasca; Alain Diaz; Maria Romero; Ana Marie Landin; Bonnie B Blomberg
Journal:  Ageing Res Rev       Date:  2010-08-20       Impact factor: 10.895

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