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Literature DB >> 787760

Modulation of RNA polymerase specificity by ppGpp.

Abstract

ppGpp alters the initiation specificity of RNA polymerase holoenzyme in vitro in a direction which mimics the stringent response in vivo. The transition temperature for opening rRNA promoters is increased by the nucleotide, that for opening phi80 promoters is unaffected. This implies that RNA polymerase can discriminate between different types of promoter. ppGpp may act by effecting a structural change in the enzyme.

Entities: Chemical Disease

Mesh：

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Year: 1976 PMID： 787760 DOI： 10.1007/bf00267575

Source DB: PubMed Journal: Mol Gen Genet ISSN： 0026-8925

15 in total

Review 1. The selectivity of transcription.

Authors: M J Chamberlin
Journal: Annu Rev Biochem Date: 1974 Impact factor: 23.643

Review 2. RNA polymerase--promoter interactions: some general principles.

Authors: A Travers
Journal: Cell Date: 1974-10 Impact factor: 41.582

3. Accumulation and turnover of guanosine tetraphosphate in Escherichia coli.

Authors: N P Fiil; K von Meyenburg; J D Friesen
Journal: J Mol Biol Date: 1972-11-28 Impact factor: 5.469

4. Studies of the binding of Escherichia coli RNA polymerase to DNA. II. The kinetics of the binding reaction.

Authors: D C Hinkle; M J Chamberlin
Journal: J Mol Biol Date: 1972-09-28 Impact factor: 5.469

5. A model for the initiation of transcription by DNA-dependent RNA polymerase from Escherichia coli.

Authors: R Schäfer; W Zillig; K Zechel
Journal: Eur J Biochem Date: 1973-03-01

6. Electron microscope heteroduplex studies of sequence relations among plasmids of Escherichia coli. VIII. The structure of bacteriophage phi 80d-3ilv+su+7, including the mapping of the ribosomal RNA genes.

Authors: E Otsubo; L Soll; R C Deonier; H J Lee; N Davidson
Journal: J Mol Biol Date: 1974-11-15 Impact factor: 5.469

7. The control of ribonucleic acid synthesis in Escherichia coli. IV. Relevance of unusual phosphorylated compounds from amino acid-starved stringent strains.

Authors: M Cashel
Journal: J Biol Chem Date: 1969-06-25 Impact factor: 5.157

8. Some physical properties of RNA polymerase.

Authors: J P Richardson
Journal: Proc Natl Acad Sci U S A Date: 1966-06 Impact factor: 11.205

9. Preferential ribosomal RNA synthesis in the lysate of Escherichia coli.

Authors: A Muto
Journal: Mol Gen Genet Date: 1975

10. Regulation of ribosomal RNA synthesis in stringent bacteria.

Authors: T D Stamato; D E Pettijohn
Journal: Nat New Biol Date: 1971-11-24

44 in total

1. Regulation of sigma factor competition by the alarmone ppGpp.

Authors: Miki Jishage; Kristian Kvint; Victoria Shingler; Thomas Nyström
Journal: Genes Dev Date: 2002-05-15 Impact factor: 11.361

2. The signal for growth rate control and stringent sensitivity in E. coli is not restricted to a particular sequence motif within the promoter region.

Authors: M Zacharias; H U Göringer; R Wagner
Journal: Nucleic Acids Res Date: 1990-11-11 Impact factor: 16.971

Review 3. Control of rRNA synthesis in Escherichia coli: a systems biology approach.

Authors: Patrick P Dennis; Mans Ehrenberg; Hans Bremer
Journal: Microbiol Mol Biol Rev Date: 2004-12 Impact factor: 11.056

4. Osmotic signal transduction to proU is independent of DNA supercoiling in Escherichia coli.

Authors: R M Ramirez; M Villarejo
Journal: J Bacteriol Date: 1991-01 Impact factor: 3.490

5. Slow switchover from host RNA synthesis to bacteriophage RNA synthesis after infection of Escherichia coli with a T4 mutant defective in the bacteriophage T4-induced unfolding of the host nucleoid.

Authors: M A Tigges; C J Bursch; D P Snustad
Journal: J Virol Date: 1977-12 Impact factor: 5.103

6. The supercoiling sensitivity of a bacterial tRNA promoter parallels its responsiveness to stringent control.

Authors: N Figueroa-Bossi; M Guérin; R Rahmouni; M Leng; L Bossi
Journal: EMBO J Date: 1998-04-15 Impact factor: 11.598

7. Chloramphenicol-induced changes in the synthesis of ribosomal, transfer, and messenger ribonucleic acids in Escherichia coli B/r.

Authors: V Shen; H Bremer
Journal: J Bacteriol Date: 1977-06 Impact factor: 3.490