Literature DB >> 7873875

The stumbler mutation maps to proximal mouse chromosome 2.

W N Frankel1, H O Sweet, M T Davisson.   

Abstract

The cerebellar mouse mutation stumbler (stu) was mapped to proximal Chromosome (Chr) 2 with a recently developed polymerase chain reaction assay for endogenous retroviruses that vary between mouse strains. The stu locus resides between the markers D2Mit5 and D2Mit7. A number of developmentally or neurologically relevant candidate genes map in this region, including Bmi1, Dbh, Grin1, Notch1, Pax8, Rxra, and Spna2. Knowing the chromosomal localization of stu should simplify maintenance of the stumbler mouse stock and also enable analysis of the cerebellar defect in presymptomatic individuals.

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Year:  1994        PMID： 7873875     DOI： 10.1007/bf00426071

Source DB:  PubMed          Journal:  Mamm Genome        ISSN： 0938-8990            Impact factor:   2.957


  27 in total

1.  A genetic map of the mouse suitable for typing intraspecific crosses.

Authors:  W Dietrich; H Katz; S E Lincoln; H S Shin; J Friedman; N C Dracopoli; E S Lander
Journal:  Genetics       Date:  1992-06       Impact factor: 4.562

2.  Interspersed repetitive element polymerase chain reaction product mapping using a mouse interspecific backcross.

Authors:  R D Cox; N G Copeland; N A Jenkins; H Lehrach
Journal:  Genomics       Date:  1991-06       Impact factor: 5.736

3.  A linkage map of endogenous murine leukemia proviruses.

Authors:  W N Frankel; J P Stoye; B A Taylor; J M Coffin
Journal:  Genetics       Date:  1990-02       Impact factor: 4.562

4.  Intracisternal A-type particle elements as genetic markers: detection by repeat element viral element amplified locus-PCR.

Authors:  N Kaushik; J P Stoye
Journal:  Mamm Genome       Date:  1994-11       Impact factor: 2.957

5.  Stumbler, a new mutant mouse with cerebellar disease.

Authors:  K W Caddy; R L Sidman; E M Eicher
Journal:  Brain Res       Date:  1981-03-09       Impact factor: 3.252

6.  Mapping of the mouse Rxr loci encoding nuclear retinoid X receptors RXR alpha, RXR beta, and RXR gamma.

Authors:  C W Hoopes; M Taketo; K Ozato; Q Liu; T A Howard; E Linney; M F Seldin
Journal:  Genomics       Date:  1992-11       Impact factor: 5.736

7.  Mapping of the human homologs of the murine paired-box-containing genes.

Authors:  A J Pilz; S Povey; P Gruss; C M Abbott
Journal:  Mamm Genome       Date:  1993       Impact factor: 2.957

8.  Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene.

Authors:  N M van der Lugt; J Domen; K Linders; M van Roon; E Robanus-Maandag; H te Riele; M van der Valk; J Deschamps; M Sofroniew; M van Lohuizen
Journal:  Genes Dev       Date:  1994-04-01       Impact factor: 11.361

9.  A molecular genetic linkage map of mouse chromosome 2.

Authors:  L D Siracusa; C M Silan; M J Justice; J A Mercer; A R Bauskin; Y Ben-Neriah; D Duboule; N D Hastie; N G Copeland; N A Jenkins
Journal:  Genomics       Date:  1990-03       Impact factor: 5.736

10.  MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations.

Authors:  E S Lander; P Green; J Abrahamson; A Barlow; M J Daly; S E Lincoln; L A Newberg; L Newburg
Journal:  Genomics       Date:  1987-10       Impact factor: 5.736
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  3 in total

1.  Cell-type specific proximity of centromeric domains of one homologue each of chromosomes 2 and 11 in nuclei of cerebellar Purkinje neurons.

Authors:  Kunjumon I Vadakkan; Baoxiang Li; Umberto De Boni
Journal:  Chromosoma       Date:  2006-06-02       Impact factor: 4.316

2.  New seizure frequency QTL and the complex genetics of epilepsy in EL mice.

Authors:  W N Frankel; A Valenzuela; C M Lutz; E W Johnson; W F Dietrich; J M Coffin
Journal:  Mamm Genome       Date:  1995-12       Impact factor: 2.957

3.  Spontaneous shaker rat mutant - a new model for X-linked tremor/ataxia.

Authors:  Karla P Figueroa; Sharan Paul; Tito Calì; Raffaele Lopreiato; Sukanya Karan; Martina Frizzarin; Darren Ames; Ginevra Zanni; Marisa Brini; Warunee Dansithong; Brett Milash; Daniel R Scoles; Ernesto Carafoli; Stefan M Pulst
Journal:  Dis Model Mech       Date:  2016-03-24       Impact factor: 5.758
  3 in total

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