PURPOSE: To test two-dimensional cardiac-gated phase-contrast (2DGPC) magnetic resonance (MR) imaging in the evaluation of cerebral arteriovenous malformations (AVMs) and the alterations in flow that accompany embolization therapy. MATERIALS AND METHODS: A 2DGPC sequence was used to measure flow velocity in the feeding vessels and corresponding contralateral vessels (CCVs) of seven patients (six men and one woman, 21-55 years of age; mean, 37 years) with cerebral AVMs and in the vessels of four healthy volunteers (all men; mean age, 22 years). RESULTS: In the patients, the flow in the feeding vessels exceeded the flow in the CCVs by a margin far greater than the asymmetry in flow in the volunteers. The mean reduction in flow after embolization was 54.9% +/- 11.1 in embolized feeding vessels (n = 6) and 5.3% +/- 2.8 in nonembolized vessels (n = 3). Postembolization flow enhancement was observed in the CCV (n = 2), which suggests a degree of autoregulatory dysfunction. CONCLUSION: This technique can be used to evaluate the flow patterns of AVMs and the hemodynamic changes that occur with embolization.
PURPOSE: To test two-dimensional cardiac-gated phase-contrast (2DGPC) magnetic resonance (MR) imaging in the evaluation of cerebral arteriovenous malformations (AVMs) and the alterations in flow that accompany embolization therapy. MATERIALS AND METHODS: A 2DGPC sequence was used to measure flow velocity in the feeding vessels and corresponding contralateral vessels (CCVs) of seven patients (six men and one woman, 21-55 years of age; mean, 37 years) with cerebral AVMs and in the vessels of four healthy volunteers (all men; mean age, 22 years). RESULTS: In the patients, the flow in the feeding vessels exceeded the flow in the CCVs by a margin far greater than the asymmetry in flow in the volunteers. The mean reduction in flow after embolization was 54.9% +/- 11.1 in embolized feeding vessels (n = 6) and 5.3% +/- 2.8 in nonembolized vessels (n = 3). Postembolization flow enhancement was observed in the CCV (n = 2), which suggests a degree of autoregulatory dysfunction. CONCLUSION: This technique can be used to evaluate the flow patterns of AVMs and the hemodynamic changes that occur with embolization.
Authors: Adriaan C G M van Es; Jeroen van der Grond; V Hester ten Dam; Anton J M de Craen; Gerard J Blauw; Rudi G J Westendorp; Faiza Admiraal-Behloul; Mark A van Buchem Journal: PLoS One Date: 2010-03-23 Impact factor: 3.240
Authors: M Markl; S Schnell; C Wu; E Bollache; K Jarvis; A J Barker; J D Robinson; C K Rigsby Journal: Clin Radiol Date: 2016-03-02 Impact factor: 2.350