Literature DB >> 7854040

An in situ hybridization study on interleukin-1 beta mRNA induced by transient forebrain ischemia in the rat brain.

K Yabuuchi1, M Minami, S Katsumata, A Yamazaki, M Satoh.   

Abstract

Expression of interleukin-1 beta (IL-1 beta) mRNA in the rat brain after transient forebrain ischemia was investigated by in situ hybridization histochemistry. Thirty min after the start of recirculation, IL-1 beta mRNA was induced in the several brain regions, including the olfactory bulb, cerebral cortex, hippocampus, striatum and thalamus where neuronal degeneration was reported to be observed after transient forebrain ischemia. The hybridization signals were observed both on the glial cells and around the vascular walls.

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Year:  1994        PMID： 7854040     DOI： 10.1016/0169-328x(94)90084-1

Source DB:  PubMed          Journal:  Brain Res Mol Brain Res        ISSN： 0169-328X


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