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Literature DB >> 20976117

Inflammation after stroke: mechanisms and therapeutic approaches.

Abstract

Reperfusion of ischemic brain can reduce injury and improve outcome, but secondary injury due to inflammatory mechanisms limits the efficacy and time window of such treatments for stroke. This review summarizes the cellular and molecular basis of inflammation in ischemic injury as well as possible therapeutic strategies.

Entities: CellLine Chemical Disease Gene Species

Year: 2010 PMID： 20976117 PMCID： PMC2956985 DOI： 10.1007/s12975-010-0023-7

Source DB: PubMed Journal: Transl Stroke Res ISSN： 1868-4483 Impact factor: 6.829

178 in total

1. Molecular characterization of an arachidonic acid epoxygenase in rat brain astrocytes.

Authors: N J Alkayed; J Narayanan; D Gebremedhin; M Medhora; R J Roman; D R Harder
Journal: Stroke Date: 1996-05 Impact factor: 7.914

2. Alternative splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificity.

Authors: T Namba; Y Sugimoto; M Negishi; A Irie; F Ushikubi; A Kakizuka; S Ito; A Ichikawa; S Narumiya
Journal: Nature Date: 1993-09-09 Impact factor: 49.962

3. Protective effect of the 20-HETE inhibitor HET0016 on brain damage after temporary focal ischemia.

Authors: Samuel M Poloyac; Yuqing Zhang; Robert R Bies; Patrick M Kochanek; Steven H Graham
Journal: J Cereb Blood Flow Metab Date: 2006-03-29 Impact factor: 6.200

4. Increases in tumor necrosis factor-alpha following transient global cerebral ischemia do not contribute to neuron death in mouse hippocampus.

Authors: Yuki Murakami; Kuniaki Saito; Akira Hara; Yuyan Zhu; Kaori Sudo; Masayuki Niwa; Hidehiko Fujii; Hisayasu Wada; Hiroshi Ishiguro; Hideki Mori; Mitsuru Seishima
Journal: J Neurochem Date: 2005-06 Impact factor: 5.372

5. The microglial reaction in the rat dorsal hippocampus following transient forebrain ischemia.

Authors: T Morioka; A N Kalehua; W J Streit
Journal: J Cereb Blood Flow Metab Date: 1991-11 Impact factor: 6.200

6. Peripheral white blood cell count in cerebral ischemic infarction.

Authors: C Pozzilli; G L Lenzi; C Argentino; L Bozzao; M Rasura; F Giubilei; C Fieschi
Journal: Acta Neurol Scand Date: 1985-05 Impact factor: 3.209

7. Inhibition of intercellular adhesion molecule-1 protein expression by antisense oligonucleotides is neuroprotective after transient middle cerebral artery occlusion in rat.

Authors: Raghu Vemuganti; Robert J Dempsey; Kellie K Bowen
Journal: Stroke Date: 2003-12-04 Impact factor: 7.914

8. Assessment of the relative contribution of COX-1 and COX-2 isoforms to ischemia-induced oxidative damage and neurodegeneration following transient global cerebral ischemia.

Authors: Eduardo Candelario-Jalil; Armando González-Falcón; Michel García-Cabrera; Dalia Alvarez; Said Al-Dalain; Gregorio Martínez; Olga Sonia León; Joe E Springer
Journal: J Neurochem Date: 2003-08 Impact factor: 5.372

Review 9. Inflammation as a therapeutic target in acute ischemic stroke treatment.

Authors: Antonino Tuttolomondo; Riccardo Di Sciacca; Domenico Di Raimondo; Chiara Renda; Antonio Pinto; Giuseppe Licata
Journal: Curr Top Med Chem Date: 2009 Impact factor: 3.295

10. Misoprostol, an anti-ulcer agent and PGE2 receptor agonist, protects against cerebral ischemia.

Authors: Jun Li; Xibin Liang; Qian Wang; Richard M Breyer; Louise McCullough; Katrin Andreasson
Journal: Neurosci Lett Date: 2008-04-20 Impact factor: 3.046

35 in total

1. Vascular Protection Following Cerebral Ischemia and Reperfusion.

Authors: Sara Morales Palomares; Marilyn J Cipolla
Journal: J Neurol Neurophysiol Date: 2011-09-20

2. Tissue kallikrein protects against ischemic stroke by suppressing TLR4/NF-κB and activating Nrf2 signaling pathway in rats.

Authors: Jiawei Yang; Jianhua Su; Fen Wan; Nan Yang; Haibo Jiang; Mingming Fang; Hang Xiao; Jun Wang; Jinrong Tang
Journal: Exp Ther Med Date: 2017-06-15 Impact factor: 2.447

3. Sirt1-ROS-TRAF6 Signaling-Induced Pyroptosis Contributes to Early Injury in Ischemic Mice.

Authors: Weijie Yan; Wei Sun; Jiahui Fan; Haiqing Wang; Song Han; Junfa Li; Yanling Yin
Journal: Neurosci Bull Date: 2020-04-06 Impact factor: 5.203

4. Astilbin attenuates cerebral ischemia/reperfusion injury by inhibiting the TLR4/MyD88/NF-κB pathway.

Authors: Jing Li; Zhaowei Gu; Yue Liu; Yu Wang; Min Zhao
Journal: Toxicol Res (Camb) Date: 2019-11-18 Impact factor: 3.524

5. Association Between Splenic Contraction and the Systemic Inflammatory Response After Acute Ischemic Stroke Varies with Age and Race.

Authors: Alicia Zha; Farhaan Vahidy; Jaskaren Randhawa; Kaushik Parsha; Thanh Bui; Jaroslaw Aronowski; Sean I Savitz
Journal: Transl Stroke Res Date: 2017-12-27 Impact factor: 6.829

10. PKC-β exacerbates in vitro brain barrier damage in hyperglycemic settings via regulation of RhoA/Rho-kinase/MLC2 pathway.

Authors: Kirtiman Srivastava; Beili Shao; Ulvi Bayraktutan
Journal: J Cereb Blood Flow Metab Date: 2013-08-21 Impact factor: 6.200