Literature DB >> 7850198

Origin and evolution of DNA associated with resistance to methicillin in staphylococci.

G L Archer1, D M Niemeyer.   

Abstract

The gene mediating resistance to methicillin in staphylococci (mecA) and its flanking sequences (mec DNA) make up a chromosomal DNA locus that is unique to methicillin-resistant bacteria; no equivalent locus exists in methicillin-susceptible cells. The origin of mec DNA is not known, but evidence supports horizontal transfer of mec DNA between different staphylococcal species and of the mecA gene between different Gram-positive genera.

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Year:  1994        PMID: 7850198     DOI: 10.1016/0966-842x(94)90608-4

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN: 0966-842X            Impact factor:   17.079


  42 in total

1.  Expression of pls, a gene closely associated with the mecA gene of methicillin-resistant Staphylococcus aureus, prevents bacterial adhesion in vitro.

Authors:  K Savolainen; L Paulin; B Westerlund-Wikström; T J Foster; T K Korhonen; P Kuusela
Journal:  Infect Immun       Date:  2001-05       Impact factor: 3.441

2.  Genetic organization of the downstream region of the mecA element in methicillin-resistant Staphylococcus aureus isolates carrying different polymorphisms of this region.

Authors:  D C Oliveira; S W Wu; H de Lencastre
Journal:  Antimicrob Agents Chemother       Date:  2000-07       Impact factor: 5.191

Review 3.  Use of the diagnostic bacteriology laboratory: a practical review for the clinician.

Authors:  W J Steinbach; A K Shetty
Journal:  Postgrad Med J       Date:  2001-03       Impact factor: 2.401

Review 4.  Molecular detection of antimicrobial resistance.

Authors:  A C Fluit; M R Visser; F J Schmitz
Journal:  Clin Microbiol Rev       Date:  2001-10       Impact factor: 26.132

5.  Recruitment of the mecA gene homologue of Staphylococcus sciuri into a resistance determinant and expression of the resistant phenotype in Staphylococcus aureus.

Authors:  S W Wu; H de Lencastre; A Tomasz
Journal:  J Bacteriol       Date:  2001-04       Impact factor: 3.490

Review 6.  Antimicrobial resistance: the example of Staphylococcus aureus.

Authors:  Franklin D Lowy
Journal:  J Clin Invest       Date:  2003-05       Impact factor: 14.808

7.  Heterogeneity of methicillin-susceptible Staphylococcus aureus strains at a German University Hospital implicates the circulating-strain pool as a potential source of emerging methicillin-resistant S. aureus clones.

Authors:  F Layer; B Ghebremedhin; W König; B König
Journal:  J Clin Microbiol       Date:  2006-06       Impact factor: 5.948

8.  Discrete steps in sensing of beta-lactam antibiotics by the BlaR1 protein of the methicillin-resistant Staphylococcus aureus bacterium.

Authors:  Kanjana Thumanu; Jooyoung Cha; Jed F Fisher; Richard Perrins; Shahriar Mobashery; Christopher Wharton
Journal:  Proc Natl Acad Sci U S A       Date:  2006-06-30       Impact factor: 11.205

9.  Rapid Identification of Vancomycin Resistant Enterococcus Faecalis Clinical Isolates using a Sugar Fermentation Method.

Authors:  Javad Raeisi; Mahnaz Saifi; Mohammad Reza Pourshafie; Mehri Habibi; Hamid Reza Mohajerani; Neda Akbari; Mohammad Reza Asadi Karam
Journal:  J Clin Diagn Res       Date:  2017-03-01

10.  Methicillin-resistant Staphylococcus aureus infections of the eye and orbit (an American Ophthalmological Society thesis).

Authors:  Preston Howard Blomquist
Journal:  Trans Am Ophthalmol Soc       Date:  2006
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