Literature DB >> 7831433

Intravenous sodium lactate decreases plasma GABA levels in man.

R Balon1, F Petty, V K Yeragani, G L Kramer, R Pohl.   

Abstract

Gamma aminobutyric acid (GABA), an inhibitory neurotransmitter, may play an important role in anxiety. We studied changes in plasma GABA levels in nine healthy subjects before and after infusions of sodium lactate and dextrose. Plasma GABA significantly decreased during infusions of sodium lactate (109.3 +/- 4.4 versus 91.6 +/- 5.1 pmol/ml; P = 0.0001) but not during infusions of dextrose.

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Year:  1993        PMID： 7831433     DOI： 10.1007/bf02251295

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  14 in total

1.  Plasma GABA in mood disorders.

Authors:  F Petty; G L Kramer; D Dunnam; A J Rush
Journal:  Psychopharmacol Bull       Date:  1990

2.  The effect of intracerebroventricularly administered GABA on brain monoamine metabolism.

Authors:  B Biswas; A Carlsson
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1977-08       Impact factor: 3.000

3.  Free and conjugated CSF and plasma GABA in Huntington's chorea.

Authors:  S Uhlhaas; H Lange; J Wappenschmidt; K Olek
Journal:  Acta Neurol Scand       Date:  1986-10       Impact factor: 3.209

4.  Rapid and sensitive ion-exchange fluorometric measurement of gamma-aminobutyric acid in physiological fluids.

Authors:  T A Hare; N V Bala Manyam
Journal:  Anal Biochem       Date:  1980-01-15       Impact factor: 3.365

5.  Measurement of gamma-aminobutyric acid (GABA) in blood.

Authors:  J W Ferkany; L A Smith; W E Seifert; R M Caprioli; S J Enna
Journal:  Life Sci       Date:  1978-06-19       Impact factor: 5.037

6.  Neurotransmitters in anxiety.

Authors:  R Hoehn-Saric
Journal:  Arch Gen Psychiatry       Date:  1982-06

7.  Is plasma GABA of peripheral origin?

Authors:  F Petty; G Kramer; M Feldman
Journal:  Biol Psychiatry       Date:  1987-06       Impact factor: 13.382

8.  The beta-receptor: isoproterenol anxiety states.

Authors:  M Rainey; E Ettedgui; B Pohl; R Balon; P Weinberg; S Yelonek; R Berchou
Journal:  Psychopathology       Date:  1984       Impact factor: 1.944

9.  Plasma GABA-like activity in response to ethanol challenge in men at high risk for alcoholism.

Authors:  H B Moss; J K Yao; M Burns; J Maddock; R E Tarter
Journal:  Biol Psychiatry       Date:  1990-03-15       Impact factor: 13.382

10.  Increase of human plasma GABA by sodium valproate.

Authors:  W Löscher; D Schmidt
Journal:  Epilepsia       Date:  1980-12       Impact factor: 5.864
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  1 in total

1.  A risk-benefit assessment of pharmacological treatments for panic disorder.

Authors:  J A Bennett; M Moioffer; S P Stanton; M Dwight; P E Keck
Journal:  Drug Saf       Date:  1998-06       Impact factor: 5.606
  1 in total

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