Literature DB >> 7830469

Experimental study of CO2 laser myringotomy with a hand-held otoscope and fiberoptic delivery system.

A DeRowe1, D Ophir, A Katzir.   

Abstract

CO2 laser myringotomy has previously been proven effective in patients with serous otitis media for short-term aeration of the middle ear. However, the system based on a microscope and a coaxially aligned laser is cumbersome and expensive. The advantage of CO2 laser energy is the high absorption coefficient in biological tissue, meaning minimal damage surrounding the desired lesion. The disadvantage is that conventional optical fibers do not transmit CO2 laser energy (lambda = 10.6 microns). We have developed a silver halide optical fiber of diameter 0.9 mm and lengths of several meters, with high transmission at 10.6 microns. Using a hand-held otoscope coupled to a fiberoptic delivery system, CO2 laser myringotomies were performed in guinea pigs. In the animal model the feasibility of the procedure was proven. Different irradiation parameters were studied and a "dose-dependent" relationship was found between the total energy used and the duration of a patent myringotomy. However, conventional histological studies failed to show a difference in circumferential damage with different energy parameters. CO2 laser myringotomy utilizing a hand-held otoscope coupled to an optical fiber capable of transmitting CO2 laser energy may prove simple and effective. The relationship between energy parameters and myringotomy patency may be instrumental in deciding on the optimal duration of aeration of the middle ear in secretory otitis media.

Entities:  

Mesh:

Year:  1994        PMID: 7830469     DOI: 10.1002/lsm.1900150303

Source DB:  PubMed          Journal:  Lasers Surg Med        ISSN: 0196-8092            Impact factor:   4.025


  4 in total

1.  Immediate tight sealing of skin incisions using an innovative temperature-controlled laser soldering device: in vivo study in porcine skin.

Authors:  David Simhon; Marisa Halpern; Tamar Brosh; Tamar Vasilyev; Avi Ravid; Tamar Tennenbaum; Zvi Nevo; Abraham Katzir
Journal:  Ann Surg       Date:  2007-02       Impact factor: 12.969

2.  Laser myringotomy in otitis media with effusion: long-term follow-up.

Authors:  Elbieta Hassmann; Boena Skotnicka; Maria Baczek; Małgorzata Piszcz
Journal:  Eur Arch Otorhinolaryngol       Date:  2003-10-09       Impact factor: 2.503

3.  Laser-assisted myringotomy versus conventional myringotomy with ventilation tube insertion in treatment of otitis media with effusion: Long-term follow-up.

Authors:  Tarek Fouad Youssef; Mohamed Rifaat Ahmed
Journal:  Interv Med Appl Sci       Date:  2013-03-19

4.  Tympanic membrane healing in myringotomies performed with argon laser or microknife: an experimental study in rats.

Authors:  Lucio Almeida Castagno; Luiz Lavinksy
Journal:  Braz J Otorhinolaryngol       Date:  2006 Nov-Dec
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.