BACKGROUND: A feedback temperature-controlled laser soldering system (TCLS) was used for bonding skin incisions on the backs of pigs. The study was aimed: 1) to characterize the optimal soldering parameters, and 2) to compare the immediate and long-term wound healing outcomes with other wound closure modalities. MATERIALS AND METHODS: A TCLS was used to bond the approximated wound margins of skin incisions on porcine backs. The reparative outcomes were evaluated macroscopically, microscopically, and immunohistochemically. RESULTS: The optimal soldering temperature was found to be 65 degrees C and the operating time was significantly shorter than with suturing. The immediate tight sealing of the wound by the TCLS contributed to rapid, high quality wound healing in comparison to Dermabond or Histoacryl cyanoacrylate glues or standard suturing. CONCLUSIONS: TCLS of incisions in porcine skin has numerous advantages, including rapid procedure and high quality reparative outcomes, over the common standard wound closure procedures. Further studies with a variety of skin lesions are needed before advocating this technique for clinical use.
BACKGROUND: A feedback temperature-controlled laser soldering system (TCLS) was used for bonding skin incisions on the backs of pigs. The study was aimed: 1) to characterize the optimal soldering parameters, and 2) to compare the immediate and long-term wound healing outcomes with other wound closure modalities. MATERIALS AND METHODS: A TCLS was used to bond the approximated wound margins of skin incisions on porcine backs. The reparative outcomes were evaluated macroscopically, microscopically, and immunohistochemically. RESULTS: The optimal soldering temperature was found to be 65 degrees C and the operating time was significantly shorter than with suturing. The immediate tight sealing of the wound by the TCLS contributed to rapid, high quality wound healing in comparison to Dermabond or Histoacryl cyanoacrylate glues or standard suturing. CONCLUSIONS:TCLS of incisions in porcine skin has numerous advantages, including rapid procedure and high quality reparative outcomes, over the common standard wound closure procedures. Further studies with a variety of skin lesions are needed before advocating this technique for clinical use.
Authors: Dirk A Hollander; Hans J Erli; Alf Theisen; Stephan Falk; Thomas Kreck; Stefan Müller Journal: Wound Repair Regen Date: 2003 Mar-Apr Impact factor: 3.617
Authors: Timothy W King; Eric M Brey; Adel A Youssef; Carol Johnston; Charles W Patrick Journal: Anal Quant Cytol Histol Date: 2002-02 Impact factor: 0.302
Authors: S Maartense; W A Bemelman; M S Dunker; C de Lint; E G J M Pierik; O R C Busch; D J Gouma Journal: Br J Surg Date: 2002-11 Impact factor: 6.939
Authors: Svetlana Basov; Amit Milstein; Erez Sulimani; Max Platkov; Eli Peretz; Marcel Rattunde; Joachim Wagner; Uri Netz; Abraham Katzir; Ilana Nisky Journal: Biomed Opt Express Date: 2018-10-19 Impact factor: 3.732