Literature DB >> 7829704

Self-perceived sensory responses to soap and synthetic detergent bars correlate with clinical signs of irritation.

F A Simion1, L D Rhein, B M Morrison, D D Scala, D M Salko, A M Kligman, G L Grove.   

Abstract

BACKGROUND: Epidemiologic studies indicate that after using soaps and other personal care products, many consumers experience irritation. In 50% of the cases the feelings of skin dryness, itching, and stinging occur in the absence of visible signs of irritation.
OBJECTIVE: We sought to determine the relation between self-perceived sensory responses of panelists to cleansing products and clinical signs of irritation.
METHODS: A combination of exaggerated arm-washing methods was designed to induce clinical signs of irritation with psychometric techniques developed to quantify sensations.
RESULTS: Two studies demonstrated that panelists could reproducibly differentiate between products on the basis of the sensations they felt and that there was a significant correlation (frequently r > 0.80) between these and the observable signs. In the case of skin dryness panelists differentiated products several washing cycles before observable differences were detected.
CONCLUSION: Sensory evaluations of irritation yield additional information on soap and detergent irritancy beyond clinical observations and expand understanding of the irritation process.

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Year:  1995        PMID: 7829704     DOI: 10.1016/0190-9622(95)90127-2

Source DB:  PubMed          Journal:  J Am Acad Dermatol        ISSN: 0190-9622            Impact factor:   11.527


  4 in total

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2.  Antimicrobial resistance patterns of colonizing flora on nurses' hands in the neonatal intensive care unit.

Authors:  Heather A Cook; Jeannie P Cimiotti; Phyllis Della-Latta; Lisa Saiman; Elaine L Larson
Journal:  Am J Infect Control       Date:  2007-05       Impact factor: 2.918

3.  Work environment and hand dermatitis among nurses in a Chinese teaching hospital.

Authors:  Derek R Smith; Ning Wei; Lin Kang; Rui-Sheng Wang
Journal:  Environ Health Prev Med       Date:  2004-07       Impact factor: 3.674

4.  Healthcare workers' hand microbiome may mediate carriage of hospital pathogens.

Authors:  Mariana Rosenthal; Allison Aiello; Elaine Larson; Carol Chenoweth; Betsy Foxman
Journal:  Pathogens       Date:  2013-12-27
  4 in total

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