| Literature DB >> 7822046 |
R Lagos1, A Avendaño, V Prado, I Horwitz, S Wasserman, G Losonsky, S Cryz, J B Kaper, M M Levine.
Abstract
Persons of blood group O are at increased risk of developing cholera gravis. In a randomized, placebo-controlled, double-blind safety-immunogenicity trial of live oral cholera vaccine CVD 103-HgR in 5- to 9-year-old Chilean children, vibriocidal antibody seroconversion (74% overall) did not differ by blood group. However, the reciprocal geometric mean titer (GMT) in blood group O vaccines (GMT = 486) was higher than that in non-O vaccines (GMT = 179) (P < 0.02).Entities:
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Year: 1995 PMID: 7822046 PMCID: PMC173056 DOI: 10.1128/iai.63.2.707-709.1995
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441