Literature DB >> 8359923

Safety, immunogenicity, and excretion pattern of single-dose live oral cholera vaccine CVD 103-HgR in Peruvian adults of high and low socioeconomic levels.

E Gotuzzo1, B Butron, C Seas, M Penny, R Ruiz, G Losonsky, C F Lanata, S S Wasserman, E Salazar, J B Kaper.   

Abstract

Groups of 122 Peruvian adults of low socioeconomic level (SEL) and 125 of high SEL received a randomly allocated 5 x 10(9)- or 5 x 10(8)-CFU dose of CVD 103-HgR live oral cholera vaccine or a placebo. The vaccine was well tolerated. Vibriocidal seroconversions occurred in 78% of high-SEL and 72% of low-SEL subjects who ingested the high dose and in 78 and 49%, respectively, of those who received the low dose.

Mesh:

Substances:

Year:  1993        PMID: 8359923      PMCID: PMC281106          DOI: 10.1128/iai.61.9.3994-3997.1993

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  17 in total

1.  Recombinant attenuated Vibrio cholerae strains used as live oral vaccines.

Authors:  J B Kaper; M M Levine
Journal:  Res Microbiol       Date:  1990 Sep-Oct       Impact factor: 3.992

2.  Field trial of oral cholera vaccines in Bangladesh: serum vibriocidal and antitoxic antibodies as markers of the risk of cholera.

Authors:  J D Clemens; F van Loon; D A Sack; J Chakraborty; M R Rao; F Ahmed; J R Harris; M R Khan; M Yunus; S Huda
Journal:  J Infect Dis       Date:  1991-06       Impact factor: 5.226

3.  Safety, immunogenicity, and efficacy of recombinant live oral cholera vaccines, CVD 103 and CVD 103-HgR.

Authors:  M M Levine; J B Kaper; D Herrington; J Ketley; G Losonsky; C O Tacket; B Tall; S Cryz
Journal:  Lancet       Date:  1988-08-27       Impact factor: 79.321

4.  Randomized double-blind placebo controlled trial to evaluate the safety and immunogenicity of the live oral cholera vaccine strain CVD 103-HgR in Swiss adults.

Authors:  S J Cryz; M M Levine; J B Kaper; E Fürer; B Althaus
Journal:  Vaccine       Date:  1990-12       Impact factor: 3.641

5.  Preliminary assessment of the safety and immunogenicity of live oral cholera vaccine strain CVD 103-HgR in healthy Thai adults.

Authors:  S Migasena; P Pitisuttitham; B Prayurahong; P Suntharasamai; W Supanaranond; V Desakorn; U Vongsthongsri; B Tall; J Ketley; G Losonsky
Journal:  Infect Immun       Date:  1989-11       Impact factor: 3.441

6.  Seroepidemiological studies of El Tor cholera in Bangladesh: association of serum antibody levels with protection.

Authors:  R I Glass; A M Svennerholm; M R Khan; S Huda; M I Huq; J Holmgren
Journal:  J Infect Dis       Date:  1985-02       Impact factor: 5.226

Review 7.  Live oral vaccines against cholera: an update.

Authors:  M M Levine; J B Kaper
Journal:  Vaccine       Date:  1993       Impact factor: 3.641

8.  Serological studies in cholera. 2. The vibriocidal antibody response of cholera patients determined by a microtechnique.

Authors:  A S Benenson; A Saad; W H Mosley
Journal:  Bull World Health Organ       Date:  1968       Impact factor: 9.408

9.  The relationship of vibriocidal antibody titre to susceptibility to cholera in family contacts of cholera patients.

Authors:  W H Mosley; S Ahmad; A S Benenson; A Ahmed
Journal:  Bull World Health Organ       Date:  1968       Impact factor: 9.408

10.  Enzyme-linked immunosorbent assay to measure antibodies to purified heat-labile enterotoxins from human and porcine strains of Escherichia coli and to cholera toxin: application in serodiagnosis and seroepidemiology.

Authors:  M M Levine; C R Young; R E Black; Y Takeda; R A Finkelstein
Journal:  J Clin Microbiol       Date:  1985-02       Impact factor: 5.948

View more
  32 in total

1.  Expanded safety and immunogenicity of a bivalent, oral, attenuated cholera vaccine, CVD 103-HgR plus CVD 111, in United States military personnel stationed in Panama.

Authors:  D N Taylor; J L Sanchez; J M Castro; C Lebron; C M Parrado; D E Johnson; C O Tacket; G A Losonsky; S S Wasserman; M M Levine; S J Cryz
Journal:  Infect Immun       Date:  1999-04       Impact factor: 3.441

2.  Improving the performance of enteric vaccines in the developing world.

Authors:  Andrew C Serazin; Laura A Shackelton; Christopher Wilson; Maharaj K Bhan
Journal:  Nat Immunol       Date:  2010-09       Impact factor: 25.606

3.  Safety and immunogenicity of single-dose live oral cholera vaccine strain CVD 103-HgR, prepared from new master and working cell banks.

Authors:  Wilbur H Chen; Richard N Greenberg; Marcela F Pasetti; Sofie Livio; Michael Lock; Marc Gurwith; Myron M Levine
Journal:  Clin Vaccine Immunol       Date:  2013-10-30

4.  Evaluation of a bivalent (CVD 103-HgR/CVD 111) live oral cholera vaccine in adult volunteers from the United States and Peru.

Authors:  D N Taylor; C O Tacket; G Losonsky; O Castro; J Gutierrez; R Meza; J P Nataro; J B Kaper; S S Wasserman; R Edelman; M M Levine; S J Cryz
Journal:  Infect Immun       Date:  1997-09       Impact factor: 3.441

5.  An overview of VaxchoraTM, a live attenuated oral cholera vaccine.

Authors:  Tarun Saluja; Vijayalaxmi V Mogasale; Jean-Louis Excler; Jerome H Kim; Vittal Mogasale
Journal:  Hum Vaccin Immunother       Date:  2019-09-20       Impact factor: 3.452

Review 6.  Performance of rotavirus vaccines in developed and developing countries.

Authors:  Victoria Jiang; Baoming Jiang; Jacqueline Tate; Umesh D Parashar; Manish M Patel
Journal:  Hum Vaccin       Date:  2010-07

Review 7.  Maximizing protection from use of oral cholera vaccines in developing country settings: an immunological review of oral cholera vaccines.

Authors:  Sachin N Desai; Alejandro Cravioto; Dipika Sur; Suman Kanungo
Journal:  Hum Vaccin Immunother       Date:  2014-05-26       Impact factor: 3.452

8.  Pediatric small intestine bacterial overgrowth in low-income countries.

Authors:  Jeffrey R Donowitz; William A Petri
Journal:  Trends Mol Med       Date:  2014-11-15       Impact factor: 11.951

Review 9.  Immunogenicity and efficacy of oral vaccines in developing countries: lessons from a live cholera vaccine.

Authors:  Myron M Levine
Journal:  BMC Biol       Date:  2010-10-04       Impact factor: 7.431

10.  Construction and evaluation of a safe, live, oral Vibrio cholerae vaccine candidate, IEM108.

Authors:  Weili Liang; Shixia Wang; Fenggang Yu; Lijuan Zhang; Guoming Qi; Yanqing Liu; Shouyi Gao; Biao Kan
Journal:  Infect Immun       Date:  2003-10       Impact factor: 3.441

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.