| Literature DB >> 7819051 |
J Adélaide1, G Monges, C Dérdérian, J F Seitz, D Birnbaum.
Abstract
The human CCND1/PRAD1 gene, located in the 11q13 chromosomal region, encodes a cyclin D protein with potential oncogenic capacity and is involved in several human malignancies. The amplification and expression status of CCND1 was investigated in a series of oesophageal tumours. CCND1 is amplified in 54% and overexpressed in 63% of the tumours of the squamous cell type.Entities:
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Year: 1995 PMID: 7819051 PMCID: PMC2033462 DOI: 10.1038/bjc.1995.13
Source DB: PubMed Journal: Br J Cancer ISSN: 0007-0920 Impact factor: 7.640