Literature DB >> 7816839

Axial skeleton homeosis and forelimb malformations in Hoxd-11 mutant mice.

B Favier1, M Le Meur, P Chambon, P Dollé.   

Abstract

The Hoxd-11 gene was disrupted by homologous recombination in embryonic stem cells. We found that Hoxd-11-/- mutant mice are viable and display homeotic transformations of their sacral vertebrae, while their forelimbs present abnormalities of some metacarpals and of the first row of carpal bones. These results are discussed in the light of current models of tetrapod axial skeleton and limb patterning.

Entities:  

Mesh：

Year:  1995        PMID： 7816839      PMCID： PMC42868          DOI： 10.1073/pnas.92.1.310

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  15 in total

1.  Coordinate expression of the murine Hox-5 complex homoeobox-containing genes during limb pattern formation.

Authors:  P Dollé; J C Izpisúa-Belmonte; H Falkenstein; A Renucci; D Duboule
Journal:  Nature       Date:  1989-12-14       Impact factor: 49.962

2.  Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression.

Authors:  T Lufkin; A Dierich; M LeMeur; M Mark; P Chambon
Journal:  Cell       Date:  1991-09-20       Impact factor: 41.582

3.  HOX-4 genes and the morphogenesis of mammalian genitalia.

Authors:  P Dollé; J C Izpisúa-Belmonte; J M Brown; C Tickle; D Duboule
Journal:  Genes Dev       Date:  1991-10       Impact factor: 11.361

4.  Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs.

Authors:  P Dollé; A Dierich; M LeMeur; T Schimmang; B Schuhbaur; P Chambon; D Duboule
Journal:  Cell       Date:  1993-11-05       Impact factor: 41.582

5.  [Morphological, histochemical and autoradiographic study of skeletogenesis in the developing limbs of the mouse embryo. I. Forelimbs].

Authors:  J Milaire
Journal:  Arch Biol (Liege)       Date:  1978

Review 6.  Positional information in chick limb morphogenesis.

Authors:  D Summerbell; J H Lewis; L Wolpert
Journal:  Nature       Date:  1973-08-24       Impact factor: 49.962

7.  Homeotic transformations and limb defects in Hox A11 mutant mice.

Authors:  K M Small; S S Potter
Journal:  Genes Dev       Date:  1993-12       Impact factor: 11.361

8.  Murine genes related to the Drosophila AbdB homeotic genes are sequentially expressed during development of the posterior part of the body.

Authors:  J C Izpisúa-Belmonte; H Falkenstein; P Dollé; A Renucci; D Duboule
Journal:  EMBO J       Date:  1991-08       Impact factor: 11.598

9.  Axial homeosis and appendicular skeleton defects in mice with a targeted disruption of hoxd-11.

Authors:  A P Davis; M R Capecchi
Journal:  Development       Date:  1994-08       Impact factor: 6.868

10.  Function of the retinoic acid receptors (RARs) during development (I). Craniofacial and skeletal abnormalities in RAR double mutants.

Authors:  D Lohnes; M Mark; C Mendelsohn; P Dollé; A Dierich; P Gorry; A Gansmuller; P Chambon
Journal:  Development       Date:  1994-10       Impact factor: 6.868
View more
  15 in total

1.  Independent regulation of vertebral number and vertebral identity by microRNA-196 paralogs.

Authors:  Siew Fen Lisa Wong; Vikram Agarwal; Jennifer H Mansfield; Nicolas Denans; Matthew G Schwartz; Haydn M Prosser; Olivier Pourquié; David P Bartel; Clifford J Tabin; Edwina McGlinn
Journal:  Proc Natl Acad Sci U S A       Date:  2015-08-17       Impact factor: 11.205

Review 2.  Molecular basis for skeletal variation: insights from developmental genetic studies in mice.

Authors:  C Kappen; A Neubüser; R Balling; R Finnell
Journal:  Birth Defects Res B Dev Reprod Toxicol       Date:  2007-12

3.  Deletion of a HoxD enhancer induces transcriptional heterochrony leading to transposition of the sacrum.

Authors:  J Zákány; M Gérard; B Favier; D Duboule
Journal:  EMBO J       Date:  1997-07-16       Impact factor: 11.598

4.  Dual role of Med12 in PRC1-dependent gene repression and ncRNA-mediated transcriptional activation.

Authors:  Thaleia Papadopoulou; Aysegül Kaymak; Sergi Sayols; Holger Richly
Journal:  Cell Cycle       Date:  2016-04-20       Impact factor: 4.534

5.  Monodactylous limbs and abnormal genitalia are associated with hemizygosity for the human 2q31 region that includes the HOXD cluster.

Authors:  M Del Campo; M C Jones; A N Veraksa; C J Curry; K L Jones; J T Mascarello; Z Ali-Kahn-Catts; T Drumheller; W McGinnis
Journal:  Am J Hum Genet       Date:  1999-07       Impact factor: 11.025

6.  The pisiform growth plate is lost in humans and supports a role for Hox in growth plate formation.

Authors:  Kelsey M Kjosness; Jasmine E Hines; C Owen Lovejoy; Philip L Reno
Journal:  J Anat       Date:  2014-10-03       Impact factor: 2.610

7.  Copy number analysis of 413 isolated talipes equinovarus patients suggests role for transcriptional regulators of early limb development.

Authors:  David M Alvarado; Jillian G Buchan; Steven L Frick; John E Herzenberg; Matthew B Dobbs; Christina A Gurnett
Journal:  Eur J Hum Genet       Date:  2012-08-15       Impact factor: 4.246

8.  Targeted disruption of Hotair leads to homeotic transformation and gene derepression.

Authors:  Lingjie Li; Bo Liu; Orly L Wapinski; Miao-Chih Tsai; Kun Qu; Jiajing Zhang; Jeff C Carlson; Meihong Lin; Fengqin Fang; Rajnish A Gupta; Jill A Helms; Howard Y Chang
Journal:  Cell Rep       Date:  2013-09-26       Impact factor: 9.423

9.  Recombineering-based dissection of flanking and paralogous Hox gene functions in mouse reproductive tracts.

Authors:  Anna M Raines; Mike Adam; Bliss Magella; Sara E Meyer; H Leighton Grimes; Sudhansu K Dey; S Steven Potter
Journal:  Development       Date:  2013-06-12       Impact factor: 6.868

Review 10.  Emerging roles for long noncoding RNAs in skeletal biology and disease.

Authors:  Nguyen P T Huynh; Britta A Anderson; Farshid Guilak; Audrey McAlinden
Journal:  Connect Tissue Res       Date:  2016-06-02       Impact factor: 3.417
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.