BACKGROUND: The incidence of malignant melanoma is increasing rapidly. The risk for development of malignant melanoma has been reported to be higher in persons of higher socioeconomic status. METHODS: This case-control study explores the relation between occupation and malignant melanoma relative risk through analysis of data collected by the American Cancer Society. A total of 1.2 million people were enrolled in a study of lifestyles and environmental factors in relation to mortality from cancer and other diseases. A total of 2780 persons had a history of malignant melanoma when the study began or developed malignant melanoma during the 6-year study follow-up period. The controls were matched for age, sex, race, and geographic location on an approximately 1:3 basis to persons selected from the remaining people enrolled. RESULTS: In men, malignant melanoma risk was significantly higher in high-paying versus low-paying occupations (odds ratio [OR], = 1.58; P < 0.001) and in white-collar versus blue-collar occupations (OR = 1.33; P < 0.001). No significant conclusions could be drawn for women. No significant difference in risk was noted between those with indoor versus outdoor occupations. Among specific occupational exposures, only exposure to X-rays significantly raised malignant melanoma risk (OR = 1.37; P = 0.002). CONCLUSION: Upper pay scale and white-collar occupations significantly increase the risk for development of malignant melanoma.
BACKGROUND: The incidence of malignant melanoma is increasing rapidly. The risk for development of malignant melanoma has been reported to be higher in persons of higher socioeconomic status. METHODS: This case-control study explores the relation between occupation and malignant melanoma relative risk through analysis of data collected by the American Cancer Society. A total of 1.2 million people were enrolled in a study of lifestyles and environmental factors in relation to mortality from cancer and other diseases. A total of 2780 persons had a history of malignant melanoma when the study began or developed malignant melanoma during the 6-year study follow-up period. The controls were matched for age, sex, race, and geographic location on an approximately 1:3 basis to persons selected from the remaining people enrolled. RESULTS: In men, malignant melanoma risk was significantly higher in high-paying versus low-paying occupations (odds ratio [OR], = 1.58; P < 0.001) and in white-collar versus blue-collar occupations (OR = 1.33; P < 0.001). No significant conclusions could be drawn for women. No significant difference in risk was noted between those with indoor versus outdoor occupations. Among specific occupational exposures, only exposure to X-rays significantly raised malignant melanoma risk (OR = 1.37; P = 0.002). CONCLUSION: Upper pay scale and white-collar occupations significantly increase the risk for development of malignant melanoma.
Authors: Erin X Wei; Abrar A Qureshi; Jiali Han; Tricia Y Li; Eunyoung Cho; Jennifer Y Lin; Wen-Qing Li Journal: J Am Acad Dermatol Date: 2016-07-16 Impact factor: 11.527
Authors: Natalie H Matthews; Michelle Koh; Wen-Qing Li; Tricia Li; Walter C Willett; Meir J Stampfer; David C Christiani; J Steven Morris; Abrar A Qureshi; Eunyoung Cho Journal: Cancer Epidemiol Biomarkers Prev Date: 2019-06-19 Impact factor: 4.254
Authors: Julia Höhn; Achim Hekler; Eva Krieghoff-Henning; Jakob Nikolas Kather; Jochen Sven Utikal; Friedegund Meier; Frank Friedrich Gellrich; Axel Hauschild; Lars French; Justin Gabriel Schlager; Kamran Ghoreschi; Tabea Wilhelm; Heinz Kutzner; Markus Heppt; Sebastian Haferkamp; Wiebke Sondermann; Dirk Schadendorf; Bastian Schilling; Roman C Maron; Max Schmitt; Tanja Jutzi; Stefan Fröhling; Daniel B Lipka; Titus Josef Brinker Journal: J Med Internet Res Date: 2021-07-02 Impact factor: 5.428