Literature DB >> 7796588

Levonorgestrel intrauterine device in the treatment of menorrhagia in Chinese women: efficacy versus acceptability.

G W Tang1, S S Lo.   

Abstract

Ten Chinese women who had menorrhagia without organic cause and suffered from anaemia were treated with levonorgestrel intrauterine device for a total of 129 woman-months. There was a 54%, 87% and 95% reduction in menstrual blood loss at the first, third and sixth month of treatment when compared with the pretreatment cycle. These percentages of reduction were statistically significant, with p values of 0.004, 0.03 and 0.008, respectively. There was a median increase in menstrual cycle length of 12 days in nine months. Fifteen percent of the menstrual cycles were longer than 60 days. The total bleeding days increased by 4 days at the third menstrual cycles, but reduced to a median of 6 days at 6 months. Seventy-six percent of the menstrual bleeding was in the form of spotting. These Chinese women accepted such menstrual alterations. There was no hormonal side effects. All women preferred the device to hysterectomy. Levonorgestrel intrauterine device appeared to be an effective and acceptable treatment for menorrhagia in perimenopausal Chinese women.

Entities:  

Keywords:  Anemia--prevention and control; Asia; Case Control Studies; Contraception; Contraceptive Agents; Contraceptive Agents, Female; Contraceptive Agents, Progestin; Contraceptive Methods; Contraceptive Usage; Developing Countries; Diseases; Eastern Asia; Family Planning; Hong Kong; Iud; Iud, Hormone Releasing; Levonorgestrel; Menorrhagia--prevention and control; Menstruation Disorders; Method Acceptability; Prospective Studies; Research Report; Studies

Mesh:

Substances:

Year:  1995        PMID: 7796588     DOI: 10.1016/0010-7824(95)00038-c

Source DB:  PubMed          Journal:  Contraception        ISSN: 0010-7824            Impact factor:   3.375


  7 in total

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Review 2.  Medical treatment of uterine leiomyoma.

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Journal:  Reprod Sci       Date:  2012-02-28       Impact factor: 3.060

3.  Therapy of heavy menstrual bleeding in Korea: Subanalysis and results from a multinational clinical trial in the Asian region investigating the levonorgestrel-releasing intrauterine system versus conventional therapy.

Authors:  Byung Seok Lee; Xu Ling; Shaheena Asif; Peter Kraemer; Jens Ulrich Hanisch; Pirjo Inki; Jung Eun Lee
Journal:  Obstet Gynecol Sci       Date:  2015-03-16

4.  Benefit-risk assessment of the levonorgestrel intrauterine system in contraception.

Authors:  Tiina Backman
Journal:  Drug Saf       Date:  2004       Impact factor: 5.606

5.  Different bleeding patterns with the use of levonorgestrel intrauterine system: are they associated with changes in uterine artery blood flow?

Authors:  Carlo Bastianelli; Manuela Farris; Stefania Rapiti; Roberta Bruno Vecchio; Giuseppe Benagiano
Journal:  Biomed Res Int       Date:  2014-04-23       Impact factor: 3.411

Review 6.  Noncontraceptive benefits of the estradiol valerate/dienogest combined oral contraceptive: a review of the literature.

Authors:  Rossella E Nappi; Marco Serrani; Jeffrey T Jensen
Journal:  Int J Womens Health       Date:  2014-08-02

Review 7.  Understanding benefits and addressing misperceptions and barriers to intrauterine device access among populations in the United States.

Authors:  Jennie Yoost
Journal:  Patient Prefer Adherence       Date:  2014-07-03       Impact factor: 2.711

  7 in total

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