Literature DB >> 7796016

Morbidity and mortality after hepatic resection of metastases from colorectal cancer.

R Doci1, L Gennari, P Bignami, F Montalto, A Morabito, F Bozzetti, M G Bonalumi.   

Abstract

A review was carried out of morbidity and mortality after hepatic resection for metastatic colorectal cancer in 208 consecutive patients who underwent this procedure between 1980 and 1992. Overall postoperative morbidity and mortality rates were 35 and 2.4 per cent respectively. The major morbidity rate was 18 per cent, the main complications being intra-abdominal sepsis, biliary fistula and haemorrhage. Of the different factors examined, morbidity was significantly related to the extent of liver resection (53 versus 21 per cent after major and minor resections respectively), amount of blood transfused (18 versus 52 per cent for no transfusion and more than 300 ml transfused respectively) and the date of the operation (53 versus 24 per cent before and after 1986 respectively). Multivariate analysis showed that only the extent of hepatic resection and the period at which surgery was performed retained their statistical significance. These data support the opinion that surgical treatment of hepatic metastases from colorectal cancer is an effective procedure with acceptable mortality and morbidity rates. An extensive experience of hepatic surgery is, however, necessary to optimize results.

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Year:  1995        PMID: 7796016     DOI: 10.1002/bjs.1800820332

Source DB:  PubMed          Journal:  Br J Surg        ISSN: 0007-1323            Impact factor:   6.939


  35 in total

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4.  Liver Metastasis from Colorectal Cancer in the Elderly: Is Surgery Justified?

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5.  Postoperative bile leakage managed successfully by intrahepatic biliary ablation with ethanol.

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6.  Is extended hepatectomy for hepatobiliary malignancy justified?

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9.  Colorectal liver metastasis surgery: analysis of risk factors predicting postoperative complications in relation to the extent of resection.

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10.  Operative terminology and post-operative management approaches applied to hepatic surgery: Trainee perspectives.

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