Literature DB >> 7795408

Importance of lectins for the prevention of bacterial infections and cancer metastases.

J Beuth1, H L Ko, G Pulverer, G Uhlenbruck, H Pichlmaier.   

Abstract

Adhesion of bacteria and of metastasizing tumour cells have much in common, especially the participation of lectins in this process. In the future it might be possible to inhibit the metastatic process and bacterial adhesion by blocking with lectins specific for appropriate (oligo) saccharides or glycoconjugates. Initial clinical trials are very promising.

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Year:  1995        PMID： 7795408     DOI： 10.1007/bf00731862

Source DB:  PubMed          Journal:  Glycoconj J        ISSN： 0282-0080            Impact factor:   2.916


  33 in total

1.  Glycoprotein modifications of sarcoma L-1 tumor cells by tunicamycin, swainsonine, bromoconduritol or 1-desoxynojirimycin treatment inhibits their metastatic lung colonization in Balb/c-mice.

Authors:  G Pulverer; J Beuth; H L Ko; A Yassin; Y Ohshima; K Roszkowski; G Uhlenbruck
Journal:  J Cancer Res Clin Oncol       Date:  1988       Impact factor: 4.553

2.  Inhibition of liver metastasis in mice by blocking hepatocyte lectins with arabinogalactan infusions and D-galactose.

Authors:  J Beuth; H L Ko; K Oette; G Pulverer; K Roszkowski; G Uhlenbruck
Journal:  J Cancer Res Clin Oncol       Date:  1987       Impact factor: 4.553

Review 3.  Lectins: their multiple endogenous cellular functions.

Authors:  S H Barondes
Journal:  Annu Rev Biochem       Date:  1981       Impact factor: 23.643

4.  In vitro and in vivo inhibition of lectin mediated adhesion of Pseudomonas aeruginosa by receptor blocking carbohydrates.

Authors:  H L Ko; J Beuth; J Sölter; H Schroten; G Uhlenbruck; G Pulverer
Journal:  Infection       Date:  1987 Jul-Aug       Impact factor: 3.553

5.  Blocking of lectin-like adhesion molecules on pulmonary cells inhibits lung sarcoma L-1 colonization in BALB/c-mice.

Authors:  W Roszkowski; J Beuth; H L Ko; G Uhlenbruck; G Pulverer
Journal:  Experientia       Date:  1989-06-15

6.  Absence of colorectal cancer metastasis to the cirrhotic liver.

Authors:  S Uetsuji; M Yamamura; K Yamamichi; Y Okuda; H Takada; K Hioki
Journal:  Am J Surg       Date:  1992-08       Impact factor: 2.565

7.  Hyperasialoglycoproteinemia in patients with chronic liver diseases and/or liver cell carcinoma. Asialoglycoprotein receptor in cirrhosis and liver cell carcinoma.

Authors:  T Sawamura; H Nakada; H Hazama; Y Shiozaki; Y Sameshima; Y Tashiro
Journal:  Gastroenterology       Date:  1984-12       Impact factor: 22.682

8.  Type of fimbriation determines adherence of Klebsiella bacteria to human epithelial cells.

Authors:  M Würker; J Beuth; H L Ko; A Przondo-Mordarska; G Pulverer
Journal:  Zentralbl Bakteriol       Date:  1990-11

9.  Studies on the binding of bacteria to glycolipids. Two species of Propionibacterium apparently recognize separate epitopes on lactose of lactosylceramide.

Authors:  N Strömberg; M Ryd; A A Lindberg; K A Karlsson
Journal:  FEBS Lett       Date:  1988-05-09       Impact factor: 4.124

10.  The role of lectins and lipoteichoic acid in adherence of Staphylococcus saprophyticus.

Authors:  J Beuth; H L Ko; Y Ohshima; A Yassin; G Uhlenbruck; G Pulverer
Journal:  Zentralbl Bakteriol Mikrobiol Hyg A       Date:  1988-05
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  4 in total

1.  Antinociceptive and anti-inflammatory effects of a mucin-binding agglutinin isolated from the red marine alga Hypnea cervicornis.

Authors:  Flávio da S Bitencourt; Jozi G Figueiredo; Mário R L Mota; Carla C R Bezerra; Priscila P Silvestre; Marcus R Vale; Kyria S Nascimento; Alexandre H Sampaio; Celso S Nagano; Silvana Saker-Sampaio; Wladimir R L Farias; Benildo S Cavada; Ana M S Assreuy; Nylane M N de Alencar
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2008-02-13       Impact factor: 3.000

Review 2.  Safe as mother's milk: carbohydrates as future anti-adhesion drugs for bacterial diseases.

Authors:  N Sharon; I Ofek
Journal:  Glycoconj J       Date:  2000 Jul-Sep       Impact factor: 2.916

3.  Radiolabeling of cramoll 1,4: evaluation of the biodistribution.

Authors:  Beatriz Ferreira de Carvalho Patricio; Maria Helena Madruga Lima-Ribeiro; Maria Tereza Dos Santos Correia; Ana Maria Dos Anjos Carneiro-Leão; Marta de Souza Albernaz; Thiago Barboza; Sergio Augusto Lopes de Souza; Ralph Santos-Oliveira
Journal:  Int J Pept       Date:  2011-06-30

4.  Antinociceptive and anti-inflammatory effects of a lectin-like substance from Clitoria fairchildiana R. Howard seeds.

Authors:  Joana Filomena Magalhães Leite; Ana Maria Sampaio Assreuy; Mário Rogério Lima Mota; Pedro Henrique de Souza Ferreira Bringel; Rodrigo Rodrigues e Lacerda; Vinícius de Morais Gomes; João Batista Cajazeiras; Kyria Santiago do Nascimento; Hilzeth de Luna Freire Pessôa; Carlos Alberto de Almeida Gadelha; Plinio Delatorre; Benildo Sousa Cavada; Tatiane Santi-Gadelha
Journal:  Molecules       Date:  2012-03-14       Impact factor: 4.411
  4 in total

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