Literature DB >> 7788305

Structurally designed novel furogamma lactams as inhibitors for bacterial propagations.

J K Ray1, I Sami, G K Kar, B C Roy, N K Brahma.   

Abstract

Some novel furogamma lactams have been synthesised by one step condensation of arylaminomalonates with substituted furyl acryloyl chlorides. The annulation of substituted monocyclic gammalactams followed by cyclization produced novel tricyclic furogamma lactams. Some of these furogammalactams are found to exhibit Gram-positive and Gram-negative antibacterial activity at very high concentrations.

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Year:  1994        PMID: 7788305     DOI: 10.1016/s0968-0896(00)82094-5

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


  2 in total

1.  1-(3-Chloro-4-fluoro-phen-yl)-5-(2-diazo-acet-yl)-4-phenyl-pyrrolidin-2-one.

Authors:  Jayanta Kumar Ray; Pranab Haldar; M Canle L; M I Fernández P; J A Santaballa
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-07-24

2.  Diethyl 1-(4-methyl-phen-yl)-3-phenyl-5-oxopyrrolidine-2,2-dicarboxyl-ate.

Authors:  Jayanta Kumar Ray; Gopa Barman; M Canle L; M I Fernández P; J A Santaballa
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-07-24
  2 in total

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