Literature DB >> 21588395

1-(3-Chloro-4-fluoro-phen-yl)-5-(2-diazo-acet-yl)-4-phenyl-pyrrolidin-2-one.

Jayanta Kumar Ray, Pranab Haldar, M Canle L, M I Fernández P, J A Santaballa.   

Abstract

In the title compound, C(18)H(13)ClFN(3)O(2), the pyrrolidine ring adopts an envelope conformation and the planar part is rotated by 4.3 (6)° from the plane of the benzene ring and is almost perperdicular both to the diazo-acetyl unit [dihedral angle = 78.93 (7)°] and the phenyl ring [dihedral angle = 86.07 (7)°]. In the crystal, mol-ecules are linked into a three-dimensional framework by C-H⋯O inter-actions. The mol-ecular conformation is stabilized by an intra-molecular C-H⋯O hydrogen bond.

Entities:  

Year:  2010        PMID: 21588395      PMCID: PMC3007471          DOI: 10.1107/S1600536810024657

Source DB:  PubMed          Journal:  Acta Crystallogr Sect E Struct Rep Online        ISSN: 1600-5368


  7 in total

1.  The Cambridge Structural Database: a quarter of a million crystal structures and rising.

Authors:  Frank H Allen
Journal:  Acta Crystallogr B       Date:  2002-05-29

2.  A short history of SHELX.

Authors:  George M Sheldrick
Journal:  Acta Crystallogr A       Date:  2007-12-21       Impact factor: 2.290

Review 3.  C-H...O and other weak hydrogen bonds. From crystal engineering to virtual screening.

Authors:  Gautam R Desiraju
Journal:  Chem Commun (Camb)       Date:  2005-05-27       Impact factor: 6.222

4.  Diethyl 1-(4-fluorophenyl)-3-(2-furyl)-5-oxopyrrolidine-2,2-dicarboxylate and diethyl 1-(3,4-dichlorophenyl)-3-(2-furyl)-5-oxopyrrolidine-2,2-dicarboxylate.

Authors:  Jayanta Kumar Ray; Pranab Haldar; M Canle L; J A Santaballa; Jose Mahía
Journal:  Acta Crystallogr C       Date:  2004-02-10       Impact factor: 1.172

5.  Synthesis of some thieno gamma lactam monocarboxylic acids with high antibacterial activity: a new look at an old molecular system.

Authors:  G K Kar; B C Roy; S D Adhikari; J K Ray; N K Brahma
Journal:  Bioorg Med Chem       Date:  1998-12       Impact factor: 3.641

6.  Structurally designed novel furogamma lactams as inhibitors for bacterial propagations.

Authors:  J K Ray; I Sami; G K Kar; B C Roy; N K Brahma
Journal:  Bioorg Med Chem       Date:  1994-12       Impact factor: 3.641

7.  Structure validation in chemical crystallography.

Authors:  Anthony L Spek
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  2009-01-20
  7 in total
  1 in total

1.  Diethyl 1-(4-methyl-phen-yl)-3-phenyl-5-oxopyrrolidine-2,2-dicarboxyl-ate.

Authors:  Jayanta Kumar Ray; Gopa Barman; M Canle L; M I Fernández P; J A Santaballa
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-07-24
  1 in total

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