Literature DB >> 7786213

Features of age-related macular degeneration in a black population. The Barbados Eye Study Group.

A P Schachat1, L Hyman, M C Leske, A M Connell, S Y Wu.   

Abstract

OBJECTIVE: To report on the frequency of features of age-related macular degeneration in a black population based on fundus photograph gradings.
DESIGN: Population-based study.
SETTING: Barbados, West Indies. STUDY POPULATION: Residents of Barbados, selected by a random sample of Barbados-born citizens, aged 40 to 84 years. MAIN OUTCOME MEASURE: Gradings from 30 degrees stereoscopic macular photographs.
RESULTS: Black participants (n = 3444) completed examinations at the study site and had gradable macular photographs in both eyes. Drusen larger than 63 microns occurred with comparable frequency in men and women. The frequency of small drusen decreased with age, while medium and large drusen were more common in older participants. Frequencies of all age-related macular degeneration-related characteristics were similar for men and women except for small drusen, which occurred more commonly in women. Confluent drusen and pigment atrophy also increased significantly with age. Exudative features occurred in 0.5% of the participants.
CONCLUSIONS: This study provides population-based data on the frequency of features of age-related macular degeneration based on photographic gradings of a black population. Features of early age-related macular degeneration were common, but appeared at a lower frequency than has been reported for white populations. Exudative disease was infrequent, occurring in about one of 200 participants.

Entities:  

Mesh:

Year:  1995        PMID: 7786213     DOI: 10.1001/archopht.1995.01100060054032

Source DB:  PubMed          Journal:  Arch Ophthalmol        ISSN: 0003-9950


  33 in total

1.  "Oxidative protector" enzymes in the macular retinal pigment epithelium of aging eyes and eyes with age-related macular degeneration.

Authors:  R N Frank
Journal:  Trans Am Ophthalmol Soc       Date:  1998

Review 2.  Macular pigment and age related macular degeneration.

Authors:  S Beatty; M Boulton; D Henson; H H Koh; I J Murray
Journal:  Br J Ophthalmol       Date:  1999-07       Impact factor: 4.638

3.  A whole-genome screen of a quantitative trait of age-related maculopathy in sibships from the Beaver Dam Eye Study.

Authors:  James H Schick; Sudha K Iyengar; Barbara E Klein; Ronald Klein; Karlie Reading; Rachel Liptak; Christopher Millard; Kristine E Lee; Sandra C Tomany; Emily L Moore; Bonnie A Fijal; Robert C Elston
Journal:  Am J Hum Genet       Date:  2003-04-24       Impact factor: 11.025

4.  Risk factors associated with age-related macular degeneration. A case-control study in the age-related eye disease study: Age-Related Eye Disease Study Report Number 3.

Authors: 
Journal:  Ophthalmology       Date:  2000-12       Impact factor: 12.079

Review 5.  Epidemiology of age-related maculopathy: a review.

Authors:  Redmer van Leeuwen; Caroline C W Klaver; Johannes R Vingerling; Albert Hofman; Paulus T V M de Jong
Journal:  Eur J Epidemiol       Date:  2003       Impact factor: 8.082

Review 6.  Therapeutic targets in age-related macular disease.

Authors:  Alan C Bird
Journal:  J Clin Invest       Date:  2010-09-01       Impact factor: 14.808

7.  Drusen prevalence and pigmentary changes in Caucasians aged 18-54 years.

Authors:  G Silvestri; M A Williams; C McAuley; K Oakes; E Sillery; D C Henderson; S Ferguson; V Silvestri; K A Muldrew
Journal:  Eye (Lond)       Date:  2012-08-17       Impact factor: 3.775

8.  The prevalence and risk factors for age-related macular degeneration in rural-urban India, Sankara Nethralaya Rural-Urban Age-related Macular degeneration study, Report No. 1.

Authors:  R Raman; S S Pal; S Ganesan; L Gella; K Vaitheeswaran; T Sharma
Journal:  Eye (Lond)       Date:  2016-02-26       Impact factor: 3.775

9.  Risk factors for age-related maculopathy.

Authors:  Paul P Connell; Pearse A Keane; Evelyn C O'Neill; Rasha W Altaie; Edward Loane; Kumari Neelam; John M Nolan; Stephen Beatty
Journal:  J Ophthalmol       Date:  2009-09-06       Impact factor: 1.909

10.  Prevalence of early and late age-related macular degeneration in India: the INDEYE study.

Authors:  Tiruvengada Krishnan; Ravilla D Ravindran; Gudlavalleti V S Murthy; Praveen Vashist; Kathryn E Fitzpatrick; R Duraisami Thulasiraj; Neena John; Giovanni Maraini; Monica Camparini; Usha Chakravarthy; Astrid E Fletcher
Journal:  Invest Ophthalmol Vis Sci       Date:  2009-08-20       Impact factor: 4.799

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