Literature DB >> 778344

Comparison of dantrolene sodium and diazepam in the treatment of spasticity.

R T Schmidt, R H Lee, R Spehlmann.   

Abstract

The effects of dantrolene sodium and diazepam were compared in a double crossover study of 42 patients with spasticity due to stable multiple sclerosis. Both drugs reduced the findings of spasticity, clonus, and hyperreflexia, and the complaints of muscle stiffness and cramping. Each drug had different side effects which suggest indications and contraindications for its use in spastic patients.

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Year:  1976        PMID： 778344      PMCID： PMC492284          DOI： 10.1136/jnnp.39.4.350

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN： 0022-3050            Impact factor:   10.154


  25 in total

1.  QUANTITATIVE CLINICAL NEUROLOGICAL TESTING. II. SOME STATISTICAL CONSIDERATIONS OF A BATTERY OF TESTS.

Authors:  J W KUZMA; W W TOURTELLOTTE; R D REMINGTON
Journal:  J Chronic Dis       Date:  1965-03

2.  FURTHER NOTES ON DISABILITY EVALUATION IN MULTIPLE SCLEROSIS, WITH SCALE MODIFICATIONS.

Authors:  J F KURTZKE
Journal:  Neurology       Date:  1965-07       Impact factor: 9.910

3.  QUANTITATIVE CLINICAL NEUROLOGICAL TESTING. I. A STUDY OF A BATTERY OF TESTS DESIGNED TO EVALUATE IN PART THE NEUROLOGICAL FUNCTION OF PATIENTS WITH MULTIPLE SCLEROSIS AND ITS USE IN A THERAPEUTIC TRIAL.

Authors:  W W TOURTELLOTTE; A F HAERER; J F SIMPSON; J W KUZMA; J SIKORSKI
Journal:  Ann N Y Acad Sci       Date:  1965-03-31       Impact factor: 5.691

4.  Clinical pharmaco--physiology of dantrolene sodium.

Authors:  R Herman; N Mayer; S A Mecomber
Journal:  Am J Phys Med       Date:  1972-12

5.  Dantrolene sodium: long-term effects in severe spasticity.

Authors:  S B Chyatte; J V Basmajian
Journal:  Arch Phys Med Rehabil       Date:  1973-07       Impact factor: 3.966

6.  Studies on the mechanism of action of dantrolene sodium. A skeletal muscle relaxant.

Authors:  K O Ellis; J F Carpenter
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1972       Impact factor: 3.000

7.  The action of a GABA derivative in human spasticity.

Authors:  D Burke; C J Andrews; L Knowles
Journal:  J Neurol Sci       Date:  1971-10       Impact factor: 3.181

8.  The effect of Dantrium on spasticity in multiple sclerosis.

Authors:  H Ladd; C Oist; B Jonsson
Journal:  Acta Neurol Scand       Date:  1974       Impact factor: 3.209

9.  Excitation-contraction uncoupling in skeletal muscle by dantrolene sodium.

Authors:  K O Ellis; S H Bryant
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1972       Impact factor: 3.000

10.  The mode of action of the gaba derivative baclofen in human spasticy.

Authors:  E Pedersen; P Arlien-Soborg; J Mai
Journal:  Acta Neurol Scand       Date:  1974       Impact factor: 3.209
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  8 in total

Review 1.  Evidence basis for treatment of spasticity.

Authors:  D M Dawson
Journal:  Curr Neurol Neurosci Rep       Date:  2001-11       Impact factor: 5.081

Review 2.  Pain Management in Multiple Sclerosis: a Review of Available Treatment Options.

Authors:  Talal Aboud; Nathaniel M Schuster
Journal:  Curr Treat Options Neurol       Date:  2019-11-27       Impact factor: 3.598

3.  Symptomatic therapy in multiple sclerosis: a review for a multimodal approach in clinical practice.

Authors:  João Carlos Correia de Sa; Laura Airas; Emmanuel Bartholome; Nikolaos Grigoriadis; Heinrich Mattle; Celia Oreja-Guevara; Jonathan O'Riordan; Finn Sellebjerg; Bruno Stankoff; Karl Vass; Agata Walczak; Heinz Wiendl; Bernd C Kieseier
Journal:  Ther Adv Neurol Disord       Date:  2011-05       Impact factor: 6.570

Review 4.  Dantrolene sodium: a review of its pharmacological properties and therapeutic efficacy in spasticity.

Authors:  R M Pinder; R N Brogden; T M Speight; G S Avery
Journal:  Drugs       Date:  1977-01       Impact factor: 9.546

5.  Relationship between plasma concentration and effect of dantrolene sodium in man.

Authors:  W J Meyler; H W Mols-Thürkow; H Wesseling
Journal:  Eur J Clin Pharmacol       Date:  1979-09       Impact factor: 2.953

Review 6.  Dantrolene. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in malignant hyperthermia, the neuroleptic malignant syndrome and an update of its use in muscle spasticity.

Authors:  A Ward; M O Chaffman; E M Sorkin
Journal:  Drugs       Date:  1986-08       Impact factor: 9.546

7.  Motor Restoration and Spasticity Management after Stroke.

Authors:  Ellen M. Deibert; Alexander W. Dromerick
Journal:  Curr Treat Options Neurol       Date:  2002-11       Impact factor: 3.598

Review 8.  Drugs used to treat spasticity.

Authors:  M Kita; D E Goodkin
Journal:  Drugs       Date:  2000-03       Impact factor: 11.431
  8 in total

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