Literature DB >> 7781

The management of ulcerative colitis.

G Watkinson.   

Abstract

The modern medical and surgical treatment of ulcerative colitis has been detailed. Whilst improvements in medical management have been few in the past decade there have been advances in dietary management and in the use of new drugs such as azathioprine and disodium cromoglycate which are currently being evaluated. Sulphasalazine remains a valuable drug in treating attacks of the disease and in preventing relapses, and its mode of action is now better understood. Steroid therapy, used orally, parenterally or topically, is of value in managing acute colitic attacks. Surgery is often required and total proctocolectomy with ileostomy remains the operation of choice. Colectomy with ileorectal anastomosis still remains a controversial operation but has its enthusiastic advocates. The interesting a new operation of proctocolectomy, with the establishment of an ileal bladder and continent ileostomy, is being assessed in Sweden and in a few centres in Britain and America.

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Year:  1976        PMID: 7781

Source DB:  PubMed          Journal:  Practitioner        ISSN: 0032-6518


  2 in total

1.  Sulphasalazine is a potent inhibitor of prostaglandin 15-hydroxydehydrogenase: possible basis for therapeutic action in ulcerative colitis.

Authors:  J R Hoult; P K Moore
Journal:  Br J Pharmacol       Date:  1978-09       Impact factor: 8.739

2.  Inflammatory bowel disease: a practical experience.

Authors:  G Cohen
Journal:  Can Fam Physician       Date:  1978-10       Impact factor: 3.275

  2 in total

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