Literature DB >> 7778264

Erratic G-->A hypermutation within a complete caprine arthritis-encephalitis virus (CAEV) provirus.

S Wain-Hobson1, P Sonigo, M Guyader, A Gazit, M Henry.   

Abstract

The complete nucleotide sequence of an integrated provirus of caprine arthritis-encephalitis virus (CAEV) has been determined. The provirus was defective due to extensive G-->A hypermutation. Rather than being a smooth phenomenon distributed throughout the genome it was highly erratic with hypermutated and normal regions being juxtaposed, probably reflecting local fluctuations in the intracellular dCTP pool during reverse transcription of the CAEV genome. The pattern of sequence variation within the surface glycoproteins differs subtly from that of the primate lentiviruses.

Entities:  

Mesh：

Substances：

Year:  1995        PMID： 7778264     DOI： 10.1006/viro.1995.1261

Source DB:  PubMed          Journal:  Virology        ISSN： 0042-6822            Impact factor:   3.616


  20 in total

1.  In vivo HIV-1 hypermutation and viral loads among antiretroviral-naive Brazilian patients.

Authors:  Mariana Leão de Lima-Stein; Wagner Tadeu Alkmim; Maria Clara de Souza Bizinoto; Luis Fernandez Lopez; Marcelo Nascimento Burattini; Juliana Terzi Maricato; Leila Giron; Maria Cecília Araripe Sucupira; Ricardo Sobhie Diaz; Luiz Mario Janini
Journal:  AIDS Res Hum Retroviruses       Date:  2014-08-25       Impact factor: 2.205

2.  Long-Range HIV Genotyping Using Viral RNA and Proviral DNA for Analysis of HIV Drug Resistance and HIV Clustering.

Authors:  Vlad Novitsky; Melissa Zahralban-Steele; Mary Fran McLane; Sikhulile Moyo; Erik van Widenfelt; Simani Gaseitsiwe; Joseph Makhema; M Essex
Journal:  J Clin Microbiol       Date:  2015-06-03       Impact factor: 5.948

Review 3.  APOBECs and virus restriction.

Authors:  Reuben S Harris; Jaquelin P Dudley
Journal:  Virology       Date:  2015-03-26       Impact factor: 3.616

4.  Monoclonal antibodies to conformational epitopes of the surface glycoprotein of caprine arthritis-encephalitis virus: potential application to competitive-inhibition enzyme-linked immunosorbent assay for detecting antibodies in goat sera.

Authors:  F Ozyörük; W P Cheevers; G A Hullinger; T C McGuire; M Hutton; D P Knowles
Journal:  Clin Diagn Lab Immunol       Date:  2001-01

5.  Exploitation of the low fidelity of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase and the nucleotide composition bias in the HIV-1 genome to alter the drug resistance development of HIV.

Authors:  J Balzarini; M J Camarasa; M J Pérez-Pérez; A San-Félix; S Velázquez; C F Perno; E De Clercq; J N Anderson; A Karlsson
Journal:  J Virol       Date:  2001-07       Impact factor: 5.103

6.  Genetic drift can dominate short-term human immunodeficiency virus type 1 nef quasispecies evolution in vivo.

Authors:  U Plikat; K Nieselt-Struwe; A Meyerhans
Journal:  J Virol       Date:  1997-06       Impact factor: 5.103

7.  Two species of Rev proteins, with distinct N termini, are expressed by caprine arthritis encephalitis virus.

Authors:  A Gazit; P Mashiah; H Kalinski; A Gast; R Rosin-Abersfeld; S R Tronick; A Yaniv
Journal:  J Virol       Date:  1996-04       Impact factor: 5.103

8.  Genomic quasispecies associated with the initiation of infection and disease in ponies experimentally infected with equine infectious anemia virus.

Authors:  D L Lichtenstein; C J Issel; R C Montelaro
Journal:  J Virol       Date:  1996-06       Impact factor: 5.103

9.  Fate of direct and inverted repeats in the RNA hypermutagenesis reaction.

Authors:  V Pezo; M A Martinez; S Wain-Hobson
Journal:  Nucleic Acids Res       Date:  1996-01-15       Impact factor: 16.971

10.  Genomic characterization of a slow/low maedi visna virus.

Authors:  Sílvia C Barros; Fernanda Ramos; Margarida Duarte; Teresa Fagulha; Benedita Cruz; Miguel Fevereiro
Journal:  Virus Genes       Date:  2004-10       Impact factor: 2.332
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.