Literature DB >> 776602

Effect of nickel chloride on primary antibody production in the spleen.

J A Graham, D E Gardner, F J Miller, M J Daniels, D L Coffin.   

Abstract

Mice immunized intraperitoneally with sheep erythrocytes were treated with nickel chloride, a common particulate air pollutant. Primary antibody production in the spleen was examined using a hemolytic plaque technique. A negative linear dose-response relationship (p is less than 0.05) was observed between the logarithm of (plaques/10(6) cells) and the nickel concentration administered. Mice injected with 3.09 mug Ni2+/g body weight displayed lymphocyte function similar to that of control mice. However, injection of 9.26-12.34 mug Ni2+/g caused significant immunosupression (p is less than 0.05).

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Year:  1975        PMID： 776602      PMCID： PMC1475024          DOI： 10.1289/ehp.7512109

Source DB:  PubMed          Journal:  Environ Health Perspect        ISSN： 0091-6765            Impact factor:   9.031


  7 in total

1.  Metal toxicity for rabbit alveolar macrophages in vitro.

Authors:  M D Waters; D E Gardner; C Aranyi; D L Coffin
Journal:  Environ Res       Date:  1975-02       Impact factor: 6.498

2.  Determination of cell viability.

Authors:  J H HANKS; J H WALLACE
Journal:  Proc Soc Exp Biol Med       Date:  1958-05

3.  Alterations in antibody response induced by chronic inhalation of SO 2 and carbon.

Authors:  A Zarkower
Journal:  Arch Environ Health       Date:  1972-07

Review 4.  A sensible look at air pollution by metals.

Authors:  H A Schroeder
Journal:  Arch Environ Health       Date:  1970-12

5.  Cellular immunity in mice chronically exposed to fresh cigarette smoke.

Authors:  W R Thomas; P G Holt; D Keast
Journal:  Arch Environ Health       Date:  1973-12

6.  Effect of trace metals on phagocytosis by alveolar macrophages.

Authors:  J A Graham; D E Gardner; M D Waters; D L Coffin
Journal:  Infect Immun       Date:  1975-06       Impact factor: 3.441

7.  Cell to cell interaction in the immune response. II. The source of hemolysin-forming cells in irradiated mice given bone marrow and thymus or thoracic duct lymphocytes.

Authors:  G F Mitchell; J F Miller
Journal:  J Exp Med       Date:  1968-10-01       Impact factor: 14.307
  7 in total
  3 in total

1.  A survey of the effect of metals on the immune response.

Authors:  L Treagan
Journal:  Biol Trace Elem Res       Date:  1979-06       Impact factor: 3.738

2.  Antibody suppression by zinc and nickel.

Authors:  S Mehrmofakham; L Treagan
Journal:  Biol Trace Elem Res       Date:  1981-03       Impact factor: 3.738

3.  Toxicological effects of nickel chloride on IgA+ B Cells and sIgA, IgA, IgG, IgM in the intestinal mucosal immunity in broilers.

Authors:  Bangyuan Wu; Hengmin Cui; Xi Peng; Jing Fang; Zhicai Zuo; Junliang Deng; Jianying Huang
Journal:  Int J Environ Res Public Health       Date:  2014-08-11       Impact factor: 3.390
  3 in total

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