Literature DB >> 24271558

Antibody suppression by zinc and nickel.

S Mehrmofakham1, L Treagan.   

Abstract

Rats were treated with zinc chloride and with nickel acetate 2 weeks prior to immunization withE. coli bacteriophageT-1; antibody titers to bacteriophageT-1 were reduced 500-2600-fold in metal-treated rats compared to titers found in untreated control animals. Examination of the effect of metal treatment on lymphocyte blastogenesis revealed a significant reduction in the number of blast cells in the spleens of metal-treated rats.

Entities:  

Year:  1981        PMID： 24271558     DOI： 10.1007/BF02789120

Source DB:  PubMed          Journal:  Biol Trace Elem Res        ISSN： 0163-4984            Impact factor:   3.738


  8 in total

1.  A survey of the effect of metals on the immune response.

Authors:  L Treagan
Journal:  Biol Trace Elem Res       Date:  1979-06       Impact factor: 3.738

2.  Inhibition of interferon synthesis in mammalian cell cultures after nickel treatment.

Authors:  L Treagan; A Furst
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1970-05

3.  Effects of heavy metal on the immune response. Preliminary findings for cadmium in rats.

Authors:  R H Jones; R L Williams; A M Jones; W C Eveland
Journal:  Proc Soc Exp Biol Med       Date:  1971-09

4.  Characterization of lymphocyte transformation induced by zinc ions.

Authors:  N A Berger; A M Skinner
Journal:  J Cell Biol       Date:  1974-04       Impact factor: 10.539

5.  [The influence of zink and lead on the formation of antibodies (author's transl)].

Authors:  H W Schlipköter; L Ghelerter; M Sonderfeld
Journal:  Zentralbl Bakteriol Orig B       Date:  1976-12

6.  Age-dependent effects of zinc on the transformation response of human lymphocytes to mitogens.

Authors:  K M Rao; S A Schwartz; R A Good
Journal:  Cell Immunol       Date:  1979-02       Impact factor: 4.868

7.  Inhibitory effect of nickel and chromium upon antibody response of rats to immunization with T-1 phage.

Authors:  R A Figoni; L Treagan
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1975-06

8.  Effect of nickel chloride on primary antibody production in the spleen.

Authors:  J A Graham; D E Gardner; F J Miller; M J Daniels; D L Coffin
Journal:  Environ Health Perspect       Date:  1975-12       Impact factor: 9.031
  8 in total

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