| Literature DB >> 7765686 |
A Farooq1, J R Hanson, Z Iqbal.
Abstract
The fungus, Cephalosporium aphidicola, has been shown to hydroxylate progesterone predominantly at the 6 beta- and 11 alpha-positions. Minor metabolites include testosterone acetate, the 20(R)-alcohol and 12 beta, 17 alpha-dihydroxy-progesterone. The sequence involves hydroxylation at 11 alpha and then 6 beta. The hydroxylations of 11 alpha- and 17 alpha-hydroxyprogesterone and of 9 beta, 10 alpha-retroprogesterone have also been examined in the light of these results.Entities:
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Year: 1994 PMID： 7765686 DOI： 10.1016/s0031-9422(00)90346-7
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072