Literature DB >> 7764216

Synthesis of 4'-C-methylnucleosides.

T Waga1, T Nishizaki, I Miyakawa, H Ohrui, H Meguro.   

Abstract

Several 4'-C-methylnucleosides were prepared. 1H-NMR studies on these nucleotides showed that they have the 3'-exo furanose ring conformation different from the 3'-endo conformation of natural nucleosides.

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Year:  1993        PMID： 7764216     DOI： 10.1271/bbb.57.1433

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN： 0916-8451            Impact factor:   2.043


  7 in total

1.  4'-C-methyl-2'-deoxyadenosine and 4'-C-ethyl-2'-deoxyadenosine inhibit HIV-1 replication.

Authors:  B Christie Vu; Paul L Boyer; Maqbool A Siddiqui; Victor E Marquez; Stephen H Hughes
Journal:  Antimicrob Agents Chemother       Date:  2011-02-22       Impact factor: 5.191

2.  In silico design of a novel nucleotide antiviral agent by free energy perturbation.

Authors:  Dharmeshkumar Patel; Bryan D Cox; Mahesh Kasthuri; Seema Mengshetti; Leda Bassit; Kiran Verma; Olivia Ollinger-Russell; Franck Amblard; Raymond F Schinazi
Journal:  Chem Biol Drug Des       Date:  2022-04-07       Impact factor: 2.873

3.  Fluorinated Nucleosides: Synthesis and Biological Implication.

Authors:  Peng Liu; Ashoke Sharon; Chung K Chu
Journal:  J Fluor Chem       Date:  2008-09       Impact factor: 2.050

4.  Development of modified nucleosides that have supremely high anti-HIV activity and low toxicity and prevent the emergence of resistant HIV mutants.

Authors:  Hiroshi Ohrui
Journal:  Proc Jpn Acad Ser B Phys Biol Sci       Date:  2011       Impact factor: 3.493

5.  Synthesis, reactivity and biological activity of 5-alkoxymethyluracil analogues.

Authors:  Lucie Brulikova; Jan Hlavac
Journal:  Beilstein J Org Chem       Date:  2011-05-26       Impact factor: 2.883

Review 6.  The evolution of antiviral nucleoside analogues: A review for chemists and non-chemists. Part II: Complex modifications to the nucleoside scaffold.

Authors:  Mary K Yates; Katherine L Seley-Radtke
Journal:  Antiviral Res       Date:  2018-12-08       Impact factor: 10.103

7.  Search for new purine- and ribose-modified adenosine analogues as selective agonists and antagonists at adenosine receptors.

Authors:  S M Siddiqi; K A Jacobson; J L Esker; M E Olah; X D Ji; N Melman; K N Tiwari; J A Secrist; S W Schneller; G Cristalli
Journal:  J Med Chem       Date:  1995-03-31       Impact factor: 7.446
  7 in total

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