Literature DB >> 19727318

Fluorinated Nucleosides: Synthesis and Biological Implication.

Peng Liu1, Ashoke Sharon, Chung K Chu.   

Abstract

Entities:  

Year:  2008        PMID： 19727318      PMCID： PMC2583432          DOI： 10.1016/j.jfluchem.2008.06.007

Source DB:  PubMed          Journal:  J Fluor Chem        ISSN： 0022-1139            Impact factor:   2.050


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  144 in total

1.  4'-Substituted nucleosides. 2. Synthesis of the nucleoside antibiotic nucleocidin.

Authors:  I D Jenkins; J P Verheyden; J G Moffatt
Journal:  J Am Chem Soc       Date:  1976-05-26       Impact factor: 15.419

2.  A 12-week clevudine therapy showed potent and durable antiviral activity in HBeAg-positive chronic hepatitis B.

Authors:  Hyo-Suk Lee; Young-Hwa Chung; Kwansik Lee; Kwan Soo Byun; Seung Woon Paik; Joon-Yeol Han; Kwon Yoo; Hee-Won Yoo; Jin Heon Lee; Byung Chul Yoo
Journal:  Hepatology       Date:  2006-05       Impact factor: 17.425

3.  Synthesis of 4'-C-methylnucleosides.

Authors:  T Waga; T Nishizaki; I Miyakawa; H Ohrui; H Meguro
Journal:  Biosci Biotechnol Biochem       Date:  1993-09       Impact factor: 2.043

4.  Stereoselective synthesis of carbocyclic L-4'-fluoro-2',3'-dideoxyadenosine

Authors: 
Journal:  Org Lett       Date:  2000-05-04       Impact factor: 6.005

5.  Fluoro carbocyclic nucleosides: synthesis and antiviral activity of 2'- and 6'-fluoro carbocyclic pyrimidine nucleosides including carbocyclic 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-methyluracil and carbocyclic 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodouracil.

Authors:  A D Borthwick; D N Evans; B E Kirk; K Biggadike; A M Exall; P Youds; S M Roberts; D J Knight; J A Coates
Journal:  J Med Chem       Date:  1990-01       Impact factor: 7.446

6.  (E)-5-(2-Bromovinyl)-2'-deoxyuridine: a potent and selective anti-herpes agent.

Authors:  E De Clercq; J Descamps; P De Somer; P J Barr; A S Jones; R T Walker
Journal:  Proc Natl Acad Sci U S A       Date:  1979-06       Impact factor: 11.205

7.  Newly synthesized L-enantiomers of 3'-fluoro-modified beta-2'-deoxyribonucleoside 5'-triphosphates inhibit hepatitis B DNA polymerases but not the five cellular DNA polymerases alpha, beta, gamma, delta, and epsilon nor HIV-1 reverse transcriptase.

Authors:  M von Janta-Lipinski; B Costisella; H Ochs; U Hübscher; P Hafkemeyer; E Matthes
Journal:  J Med Chem       Date:  1998-06-04       Impact factor: 7.446

8.  Bicyclic nucleoside inhibitors of varicella-zoster virus: synthesis and biological evaluation of 2',3'-dideoxy-3'-fluoro and 2'-deoxy-xylo derivatives.

Authors:  A Carangio; C McGuigan; G Andrei; R Snoeck; E De Clercq; J Balzarini
Journal:  Nucleosides Nucleotides Nucleic Acids       Date:  2003 May-Aug       Impact factor: 1.381

9.  Synthesis and biological activity of 5-fluorotubercidin.

Authors:  Xiaojing Wang; Punit P Seth; Ray Ranken; Eric E Swayze; Michael T Migawa
Journal:  Nucleosides Nucleotides Nucleic Acids       Date:  2004       Impact factor: 1.381

10.  Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B.

Authors:  R McKenzie; M W Fried; R Sallie; H Conjeevaram; A M Di Bisceglie; Y Park; B Savarese; D Kleiner; M Tsokos; C Luciano
Journal:  N Engl J Med       Date:  1995-10-26       Impact factor: 91.245
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  31 in total

1.  From bifunctional to trifunctional (tricomponent nucleophile-transition metal-lewis acid) catalysis: the catalytic, enantioselective α-fluorination of acid chlorides.

Authors:  Jeremy Erb; Daniel H Paull; Travis Dudding; Lee Belding; Thomas Lectka
Journal:  J Am Chem Soc       Date:  2011-04-22       Impact factor: 15.419

2.  Thiophene-expanded guanosine analogues of Gemcitabine.

Authors:  Zhe Chen; Therese C Ku; Katherine L Seley-Radtke
Journal:  Bioorg Med Chem Lett       Date:  2015-07-30       Impact factor: 2.823

3.  Halogen Bond Interactions of Novel HIV-1 Protease Inhibitors (PI) (GRL-001-15 and GRL-003-15) with the Flap of Protease Are Critical for Their Potent Activity against Wild-Type HIV-1 and Multi-PI-Resistant Variants.

Authors:  Shin-Ichiro Hattori; Hironori Hayashi; Haydar Bulut; Kalapala Venkateswara Rao; Prasanth R Nyalapatla; Kazuya Hasegawa; Manabu Aoki; Arun K Ghosh; Hiroaki Mitsuya
Journal:  Antimicrob Agents Chemother       Date:  2019-05-24       Impact factor: 5.191

4.  Novel Central Nervous System (CNS)-Targeting Protease Inhibitors for Drug-Resistant HIV Infection and HIV-Associated CNS Complications.

Authors:  Masayuki Amano; Pedro Miguel Salcedo-Gómez; Ravikiran S Yedidi; Rui Zhao; Hironori Hayashi; Kazuya Hasegawa; Tomofumi Nakamura; Cuthbert D Martyr; Arun K Ghosh; Hiroaki Mitsuya
Journal:  Antimicrob Agents Chemother       Date:  2019-06-24       Impact factor: 5.191

5.  Broad-Spectrum Antiviral Activity of 3'-Deoxy-3'-Fluoroadenosine against Emerging Flaviviruses.

Authors:  Luděk Eyer; Pavel Svoboda; Jan Balvan; Tomáš Vičar; Matina Raudenská; Michal Štefánik; Jan Haviernik; Ivana Huvarová; Petra Straková; Ivo Rudolf; Zdeněk Hubálek; Katherine Seley-Radtke; Erik de Clercq; Daniel Růžek
Journal:  Antimicrob Agents Chemother       Date:  2021-01-20       Impact factor: 5.191

6.  Base-catalyzed diastereoselective trimerization of trifluoroacetone.

Authors:  Anthony P Silvestri; Philip E Dawson
Journal:  Org Biomol Chem       Date:  2017-06-08       Impact factor: 3.876

7.  HIV-Associated Neurocognitive Disorder (HAND) and the Prospect of Brain-Penetrating Protease Inhibitors for Antiretroviral Treatment.

Authors:  Arun K Ghosh; Anindya Sarkar; Hiroaki Mitsuya
Journal:  Med Res Arch       Date:  2017-04-15

8.  Synthesis and antiviral evaluation of 2',2',3',3'-tetrafluoro nucleoside analogs.

Authors:  Ozkan Sari; Leda Bassit; Christina Gavegnano; Tamara R McBrayer; Louise McCormick; Bryan Cox; Steven J Coats; Franck Amblard; Raymond F Schinazi
Journal:  Tetrahedron Lett       Date:  2017-01-04       Impact factor: 2.415

9.  Investigation and conformational analysis of fluorinated nucleoside antibiotics targeting siderophore biosynthesis.

Authors:  Surendra Dawadi; Kishore Viswanathan; Helena I Boshoff; Clifton E Barry; Courtney C Aldrich
Journal:  J Org Chem       Date:  2015-04-30       Impact factor: 4.354

10.  Raising the pKa limit of "soft" nucleophiles in palladium-catalyzed allylic substitutions: application of diarylmethane pronucleophiles.

Authors:  Sheng-Chun Sha; Jiadi Zhang; Patrick J Carroll; Patrick J Walsh
Journal:  J Am Chem Soc       Date:  2013-11-12       Impact factor: 15.419
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