Literature DB >> 7755168

Future directions in antler research.

R J Goss1.   

Abstract

Through a series of interrogatories, unsolved problems of antler evolution, anatomy, development, physiology, and pathology are probed, with commentaries, on the following prospects for future research: 1. How could these improbable appendages have evolved mechanisms to commit suicide, jettison the corpse, and regenerate new ones every year? 2. By what developmental processes are antlers able to prescribe their own morphogenesis with mirror image accuracy year after year and in some cases produce deliberate asymmetries? 3. What causes the scalp to transform into velvet skin as a deer's first antlers develop? 4. Why do healing pedicle stumps give rise to antler buds instead of scar tissue? 5. How is the unprecedented rate of antler elongation related to the diameter and length of the structure to be grown? 6. How come wound healing by pedicle skin is held in abeyance for several months until new growth resumes? 7. How is it that tropical deer regenerate antlers at any time of year, while in temperate zones deer do so in seasonal unison? 8. How do deer find enough calcium to make such massive antlers in only a few months? 9. What is the nature of the bizarre tumors that some antlers grow following castration?

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Year:  1995        PMID: 7755168     DOI: 10.1002/ar.1092410302

Source DB:  PubMed          Journal:  Anat Rec        ISSN: 0003-276X


  21 in total

1.  MicroRNA profiling of antler stem cells in potentiated and dormant states and their potential roles in antler regeneration.

Authors:  Hengxing Ba; Datao Wang; Chunyi Li
Journal:  Mol Genet Genomics       Date:  2016-01-06       Impact factor: 3.291

Review 2.  Deer antlers: a zoological curiosity or the key to understanding organ regeneration in mammals?

Authors:  J S Price; S Allen; C Faucheux; T Althnaian; J G Mount
Journal:  J Anat       Date:  2005-11       Impact factor: 2.610

Review 3.  Tissue engineering of replacement skin: the crossroads of biomaterials, wound healing, embryonic development, stem cells and regeneration.

Authors:  Anthony D Metcalfe; Mark W J Ferguson
Journal:  J R Soc Interface       Date:  2007-06-22       Impact factor: 4.118

Review 4.  The contribution of deer velvet antler research to the modern biological medicine.

Authors:  Yu-Shu Huo; Hong Huo; Jie Zhang
Journal:  Chin J Integr Med       Date:  2014-10-16       Impact factor: 1.978

5.  Identification of interactive molecules between antler stem cells and dermal papilla cells using an in vitro co-culture system.

Authors:  Hongmei Sun; Zhigang Sui; Datao Wang; Hengxing Ba; Haiping Zhao; Lihua Zhang; Chunyi Li
Journal:  J Mol Histol       Date:  2019-12-19       Impact factor: 2.611

6.  Mapping the morphogenetic potential of antler fields through deleting and transplanting subregions of antlerogenic periosteum in sika deer (Cervus nippon).

Authors:  Zhiguang Gao; Fuhe Yang; Chris McMahon; Chunyi Li
Journal:  J Anat       Date:  2011-11-28       Impact factor: 2.610

7.  Substances for regenerative wound healing during antler renewal stimulated scar-less restoration of rat cutaneous wounds.

Authors:  Qianqian Guo; Zhen Liu; Junjun Zheng; Haiping Zhao; Chunyi Li
Journal:  Cell Tissue Res       Date:  2021-08-14       Impact factor: 5.249

Review 8.  Exploring the mechanisms regulating regeneration of deer antlers.

Authors:  J Price; S Allen
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2004-05-29       Impact factor: 6.237

9.  Localization and characterization of STRO-1 cells in the deer pedicle and regenerating antler.

Authors:  Hans J Rolf; Uwe Kierdorf; Horst Kierdorf; Jutta Schulz; Natascha Seymour; Henning Schliephake; Joanna Napp; Sabine Niebert; Helmuth Wölfel; K Günter Wiese
Journal:  PLoS One       Date:  2008-04-30       Impact factor: 3.240

10.  A cellular, molecular, and pharmacological basis for appendage regeneration in mice.

Authors:  Thomas H Leung; Emily R Snyder; Yinghua Liu; Jing Wang; Seung K Kim
Journal:  Genes Dev       Date:  2015-10-15       Impact factor: 11.361

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