Literature DB >> 775296

Genetic and biochemical studies of phosphomannose isomerase deficient mutants of Saccharomyces cerevisiae.

L S Herrera, C Pascual, X Alvarez.   

Abstract

Three mannose-negative mutants of Saccharomyces cerevisiae have been isolated. These mutants showed growth inhibition when mannose was added to a growth medium containing glycerol or fructose. Crosses between wild type mutants showed segregation of 2+/2-. Crosses between the mutants themselves showed that they were closely linked. Two mutants (XM3 and D2) showed characteristics of allelic structural alteration of phosphomannoseisomerase. Mutant D4 had a deficiency of phosphomannoseisomerase activity, but with a normal thermostability. Revertants from D4 had a normal thermostability.

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Year:  1976        PMID： 775296     DOI： 10.1007/bf02428113

Source DB:  PubMed          Journal:  Mol Gen Genet        ISSN： 0026-8925


  15 in total

1.  Use of snail digestive juice in isolation of yeast spore tetrads.

Authors:  J R JOHNSTON; R K MORTIMER
Journal:  J Bacteriol       Date:  1959-08       Impact factor: 3.490

2.  Chromosome Mapping in Saccharomyces: Centromere-Linked Genes.

Authors:  D C Hawthorne; R K Mortimer
Journal:  Genetics       Date:  1960-08       Impact factor: 4.562

3.  Biochemical Mutants in the Smut Fungus Ustilago Maydis.

Authors:  D D Perkins
Journal:  Genetics       Date:  1949-09       Impact factor: 4.562

4.  Genetic and biochemical studies on mannose-negative mutants that are deficient in phosphomannose isomerase in Escherichia coli K-12.

Authors:  A Markovitz; R J Sydiskis; M M Lieberman
Journal:  J Bacteriol       Date:  1967-11       Impact factor: 3.490

5.  Selection of Escherichia coli mutants lacking glucose-6-phosphate dehydrogenase or gluconate-6-phosphate dehydrogenase.

Authors:  D G Fraenkel
Journal:  J Bacteriol       Date:  1968-04       Impact factor: 3.490

6.  Glucose and fructose metabolism in a phosphoglucoisomeraseless mutant of Saccharomyces cerevisiae.

Authors:  P K Maitra
Journal:  J Bacteriol       Date:  1971-09       Impact factor: 3.490

7.  Amino sugar sensitivity in Escherichia coli mutants unable to grow on N-acetylglucosamine.

Authors:  N J Bernheim; W J Dobrogosz
Journal:  J Bacteriol       Date:  1970-02       Impact factor: 3.490

8.  Induction of capsular polysaccharide synthesis by rho-fluorophenylalanine in Escherichia coli wild type and strains with altered phenylalanyl soluble ribonucleic acid synthetase.

Authors:  S Kang; A Markovitz
Journal:  J Bacteriol       Date:  1967-02       Impact factor: 3.490

9.  Glucose and gluconate metabolism in an Escherichia coli mutant lacking phosphoglucose isomerase.

Authors:  D G Fraenkel; S R Levisohn
Journal:  J Bacteriol       Date:  1967-05       Impact factor: 3.490

10.  Effect of 2-deoxyglucose on Schizosaccharomyces pombe.

Authors:  R Megnet
Journal:  J Bacteriol       Date:  1965-10       Impact factor: 3.490
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  8 in total

1.  A novel Saccharomyces cerevisiae secretory mutant possesses a thermolabile phosphomannose isomerase.

Authors:  M A Payton; M Rheinnecker; L S Klig; M DeTiani; E Bowden
Journal:  J Bacteriol       Date:  1991-03       Impact factor: 3.490

2.  Use of permeabilized yeast cells as a system of enzyme immobilization. Its use for the preparation of mannose 6-phosphate.

Authors:  C Pascual; L Herrera
Journal:  Folia Microbiol (Praha)       Date:  1981       Impact factor: 2.099

3.  Isolation and characterization of a Saccharomyces cerevisiae mutant deficient in pyruvate kinase activity.

Authors:  G F Sprague
Journal:  J Bacteriol       Date:  1977-04       Impact factor: 3.490

4.  Genetic and biochemical studies on mannose-negative mutants with colonial morphological alterations.

Authors:  E D Thompson; L W Parks
Journal:  Mol Gen Genet       Date:  1976-12-08

5.  Characterization of a regulatory mutant of fructose 1,6-bisphosphatase in Saccharomyces carlsbergensis.

Authors:  K W van de Poll; D H Schamhart
Journal:  Mol Gen Genet       Date:  1977-07-07

6.  Transport and catabolism of D-mannose in Rhizobium meliloti.

Authors:  A Arias; A Gardiol; G Martínez-Drets
Journal:  J Bacteriol       Date:  1982-09       Impact factor: 3.490

7.  A simple procedure to obtain yeast hexokinase free of glucosephosphate isomerase and mannosephosphate isomerase.

Authors:  V Cabrera; C Pascual; L S Herrera
Journal:  Folia Microbiol (Praha)       Date:  1981       Impact factor: 2.099

8.  Cloning of Escherichia coli and Pseudomonas aeruginosa phosphomannose isomerase genes and their expression in alginate-negative mutants of Pseudomonas aeruginosa.

Authors:  A Darzins; L L Nixon; R I Vanags; A M Chakrabarty
Journal:  J Bacteriol       Date:  1985-01       Impact factor: 3.490
  8 in total

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