Literature DB >> 7743594

Cost-saving through microscopy-based versus presumptive diagnosis of malaria in adult outpatients in Malawi.

A Jonkman1, R A Chibwe, C O Khoromana, U L Liabunya, M E Chaponda, G E Kandiero, M E Molyneux, T E Taylor.   

Abstract

The cost implications of changing from a policy of presumptive diagnosis to one of microscopy-based diagnosis in the management of uncomplicated malaria in an urban hospital adult outpatient clinic in Malawi were studied. Costs were measured in three separate weeks during the rainy season. In weeks I and II all uncomplicated malaria cases were treated on the basis of a presumptive diagnosis. In week II, blood films were taken but the results were not made available and did not affect drug dispensing. In week III, antimalarial drugs were restricted to parasitaemic patients. In week I, a total of 7216 prescriptions were written and dispensed, of which 2883 (39.9%) were for antimalarial drugs. The proportion of antimalarial prescriptions fell to 1171/5556 (21.1%) in week II and 357/5377 (6.6%) in week III. We estimate annual savings from microscopy-directed treatment in this setting to be 52,000 Malawi kwacha (US$ 14,000). This represents 3% of the annual drugs budget for the hospital, and is large enough to justify a change in policy.

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Year:  1995        PMID: 7743594      PMCID: PMC2486756     

Source DB:  PubMed          Journal:  Bull World Health Organ        ISSN: 0042-9686            Impact factor:   9.408


  5 in total

1.  Presumptive diagnosis of malaria results in a significant risk of mistreatment of children in urban Sahel.

Authors:  M Olivar; M Develoux; A Chegou Abari; L Loutan
Journal:  Trans R Soc Trop Med Hyg       Date:  1991 Nov-Dec       Impact factor: 2.184

Review 2.  The dynamics of drug resistance in Plasmodium falciparum.

Authors:  W H Wernsdorfer; D Payne
Journal:  Pharmacol Ther       Date:  1991       Impact factor: 12.310

3.  Epidemiological basis for clinical diagnosis of childhood malaria in endemic zone in West Africa.

Authors:  A Rougemont; N Breslow; E Brenner; A L Moret; O Dumbo; A Dolo; G Soula; L Perrin
Journal:  Lancet       Date:  1991-11-23       Impact factor: 79.321

4.  Usefulness of clinical case-definitions in guiding therapy for African children with malaria or pneumonia.

Authors:  S C Redd; P B Bloland; P N Kazembe; E Patrick; R Tembenu; C C Campbell
Journal:  Lancet       Date:  1992-11-07       Impact factor: 79.321

5.  Clinical features and prognostic indicators in paediatric cerebral malaria: a study of 131 comatose Malawian children.

Authors:  M E Molyneux; T E Taylor; J J Wirima; A Borgstein
Journal:  Q J Med       Date:  1989-05
  5 in total
  25 in total

1.  Admission diagnosis of cerebral malaria in adults in an endemic area of Tanzania: implications and clinical description.

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Journal:  QJM       Date:  2003-05

2.  The impact of response to the results of diagnostic tests for malaria: cost-benefit analysis.

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Journal:  BMJ       Date:  2008-01-16

3.  Clinical algorithm for malaria during low and high transmission seasons.

Authors:  L Muhe; B Oljira; H Degefu; F Enquesellassie; M W Weber
Journal:  Arch Dis Child       Date:  1999-09       Impact factor: 3.791

4.  Quality of malaria microscopy in 12 district hospital laboratories in Tanzania.

Authors:  Hilda Mbakilwa; Chacha Manga; Stafford Kibona; Frank Mtei; Judith Meta; Aikande Shoo; Ben Amos; Hugh Reyburn
Journal:  Pathog Glob Health       Date:  2012-10       Impact factor: 2.894

5.  Economic implications of resistance to antimalarial drugs.

Authors:  M Phillips; P A Phillips-Howard
Journal:  Pharmacoeconomics       Date:  1996-09       Impact factor: 4.981

6.  Factoring quality laboratory diagnosis into the malaria control agenda for sub-Saharan Africa.

Authors:  Michael Aidoo
Journal:  Am J Trop Med Hyg       Date:  2013-09       Impact factor: 2.345

7.  Availability of antimalarial drugs and evaluation of the attitude and practices for the treatment of uncomplicated malaria in bangui, central african republic.

Authors:  Alexandre Manirakiza; Siméon Pierre Njuimo; Alain Le Faou; Denis Malvy; Pascal Millet
Journal:  J Trop Med       Date:  2010-03-14

8.  Cost savings with rapid diagnostic tests for malaria in low-transmission areas: evidence from Dar es Salaam, Tanzania.

Authors:  Joshua Yukich; Valerie D'Acremont; Judith Kahama; Ndeniria Swai; Christian Lengeler
Journal:  Am J Trop Med Hyg       Date:  2010-07       Impact factor: 2.345

9.  Cost-effectiveness of malaria diagnostic methods in sub-Saharan Africa in an era of combination therapy.

Authors:  Samuel Shillcutt; Chantal Morel; Catherine Goodman; Paul Coleman; David Bell; Christopher J M Whitty; A Mills
Journal:  Bull World Health Organ       Date:  2008-02       Impact factor: 9.408

10.  Malaria diagnosis by a polymerase chain reaction-based assay using a pooling strategy.

Authors:  Ajay R Bharti; Scott L Letendre; Kailash P Patra; Joseph M Vinetz; Davey M Smith
Journal:  Am J Trop Med Hyg       Date:  2009-11       Impact factor: 2.345

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