Literature DB >> 7742450

Herpes simplex virus infections of the central nervous system: therapeutic and diagnostic considerations.

R J Whitley1, F Lakeman.   

Abstract

Herpes simplex virus infections of the central nervous system remain a significant cause of morbidity and mortality, in spite of safe and efficacious antiviral therapy. Advances in the treatment of neonatal herpes and herpes simplex encephalitis with acyclovir have improved outcome. The application of polymerase chain reaction has allowed for the prompt and specific diagnosis of herpes simplex virus infections of the brain. This review summarizes our current knowledge on the pathogenesis, diagnosis, and treatment of herpes simplex virus infections of the brain. Opportunities for the future will be defined.

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Year:  1995        PMID: 7742450     DOI: 10.1093/clinids/20.2.414

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN: 1058-4838            Impact factor:   9.079


  61 in total

Review 1.  The role of DNA amplification technology in the diagnosis of infectious diseases.

Authors:  M Louie; L Louie; A E Simor
Journal:  CMAJ       Date:  2000-08-08       Impact factor: 8.262

2.  Performance and use of a ribonucleotide reductase herpes simplex virus type-specific serological assay.

Authors:  S Q Wales; C C Smith; M Wachsman; G Calton; L Aurelian
Journal:  Clin Diagn Lab Immunol       Date:  2004-01

Review 3.  Admission to neurological intensive care: who, when, and why?

Authors:  Robin S Howard; Dimitri M Kullmann; Nicholas P Hirsch
Journal:  J Neurol Neurosurg Psychiatry       Date:  2003-09       Impact factor: 10.154

4.  Herpes simplex virus encephalistis during immunosuppressive treatment of ulcerative colitis.

Authors:  Seyed Meysam Alimohamadi; Reza Malekzadeh; Seyed Hossein Mirmadjless; Mehdi Mohamadnejad; Farhad Zamani
Journal:  MedGenMed       Date:  2004-11-10

5.  Diagnosis, epidemiology and pathogenesis of bacterial infections in the molecular era.

Authors:  S Sethi; T F Murphy; K L Klingman
Journal:  Clin Mol Pathol       Date:  1996-02

6.  Invader plus method detects herpes simplex virus in cerebrospinal fluid and simultaneously differentiates types 1 and 2.

Authors:  Hatim T Allawi; Haijing Li; Tamara Sander; Azamat Aslanukov; Victor I Lyamichev; Amondrea Blackman; Slava Elagin; Yi-Wei Tang
Journal:  J Clin Microbiol       Date:  2006-09       Impact factor: 5.948

7.  Predictors of outcome in acute encephalitis.

Authors:  Kiran T Thakur; Melissa Motta; Anthony O Asemota; Hannah L Kirsch; David R Benavides; Eric B Schneider; Justin C McArthur; Romergryko G Geocadin; Arun Venkatesan
Journal:  Neurology       Date:  2013-07-26       Impact factor: 9.910

Review 8.  Herpes simplex virus infections and Alzheimer's disease. Implications for drug treatment and immunotherapy.

Authors:  M A Leissring; M C Sugarman; F M LaFerla
Journal:  Drugs Aging       Date:  1998-09       Impact factor: 3.923

9.  Herpes simplex meningitis after surgical removal of a clivus chordoma.

Authors:  F Najioullah; S Ayari; D Thouvenot; C Dubreuil; M Aymard; B Lina
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1997-04       Impact factor: 3.267

10.  Effect of combinations of antiviral drugs on herpes simplex encephalitis.

Authors:  Bryan M Gebhardt; Federico Focher; Richard Eberle; Andrzej Manikowski; George E Wright
Journal:  Drug Des Devel Ther       Date:  2009-12-29       Impact factor: 4.162

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