Literature DB >> 7739000

Expedient method for the solid-phase synthesis of aspartic acid protease inhibitors directed toward the generation of libraries.

E K Kick1, J A Ellman.   

Abstract

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Year:  1995        PMID： 7739000     DOI： 10.1021/jm00009a002

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  12 in total

1.  Combinatorial chemistry and high-throughput screening in drug discovery: different strategies and formats.

Authors:  P Seneci; S Miertus
Journal:  Mol Divers       Date:  2000       Impact factor: 2.943

2.  Unraveling principles of lead discovery: from unfrustrated energy landscapes to novel molecular anchors.

Authors:  P A Rejto; G M Verkhivker
Journal:  Proc Natl Acad Sci U S A       Date:  1996-08-20       Impact factor: 11.205

3.  CombiDOCK: structure-based combinatorial docking and library design.

Authors:  Y Sun; T J Ewing; A G Skillman; I D Kuntz
Journal:  J Comput Aided Mol Des       Date:  1998-11       Impact factor: 3.686

Review 4.  Synthetic library techniques: subjective (biased and generic) thoughts and views.

Authors:  V Krchnák; M Lebl
Journal:  Mol Divers       Date:  1996-05       Impact factor: 2.943

Review 5.  Discovery of enzyme inhibitors through combinatorial chemistry.

Authors:  R E Dolle
Journal:  Mol Divers       Date:  1997       Impact factor: 2.943

6.  Combinatorial thinking in chemistry and biology.

Authors:  J Ellman; B Stoddard; J Wells
Journal:  Proc Natl Acad Sci U S A       Date:  1997-04-01       Impact factor: 11.205

7.  Conformationally restricted dipeptide amides as potent and selective neuronal nitric oxide synthase inhibitors.

Authors:  Haitao Ji; José A Gómez-Vidal; Pavel Martasek; Linda J Roman; Richard B Silverman
Journal:  J Med Chem       Date:  2006-10-19       Impact factor: 7.446

8.  Synthesis of peptidomimetics using a polymer-bound Boc-linker.

Authors:  T Redemann; H Bandel; G Jung
Journal:  Mol Divers       Date:  1998       Impact factor: 2.943

9.  New cathepsin D inhibitor library utilizing hydroxyethyl isosteres with cyclic tertiary amines.

Authors:  Rose M McConnell; Kalyani Inapudi; Naveen Kadasala; Karthika Yarlagadda; Priya Velusamy; Matthew S McConnell; Adam Green; Carol Trana; Kelley Sayyar; James S McConnell
Journal:  Med Chem       Date:  2012-11       Impact factor: 2.745

10.  Solid-phase synthesis of a thymidinyl dipeptide urea library.

Authors:  Dianqing Sun; Richard E Lee
Journal:  J Comb Chem       Date:  2007-04-07
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