Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Synthetic library techniques: subjective (biased and generic) thoughts and views.

Literature DB >> 9237211

Synthetic library techniques: subjective (biased and generic) thoughts and views.

Abstract

Various aspects of synthetic diversity generation and screening are discussed. Controversial issues are raised and different points of view are presented. We hope the article will stimulate thinking about the utilization of library techniques and start a discussion about questions concerning their application.

Mesh：

Substances：

Year: 1996 PMID： 9237211 DOI： 10.1007/bf01544958

Source DB: PubMed Journal: Mol Divers ISSN： 1381-1991 Impact factor: 2.943

61 in total

Review 1. Discovering peptide ligands using epitope libraries.

Authors: J K Scott
Journal: Trends Biochem Sci Date: 1992-07 Impact factor: 13.807

2. Evaluation of peptide libraries: an iterative strategy to analyze the reactivity of peptide mixtures with antibodies.

Authors: J Blake; L Litzi-Davis
Journal: Bioconjug Chem Date: 1992 Nov-Dec Impact factor: 4.774

3. A new type of synthetic peptide library for identifying ligand-binding activity.

Authors: K S Lam; S E Salmon; E M Hersh; V J Hruby; W M Kazmierski; R J Knapp
Journal: Nature Date: 1991-11-07 Impact factor: 49.962

4. Complex synthetic chemical libraries indexed with molecular tags.

Authors: M H Ohlmeyer; R N Swanson; L W Dillard; J C Reader; G Asouline; R Kobayashi; M Wigler; W C Still
Journal: Proc Natl Acad Sci U S A Date: 1993-12-01 Impact factor: 11.205

5. The discovery of librium.

Authors: L H Sternbach
Journal: Agents Actions Date: 1972-06

6. Application of a dual color detection scheme in the screening of a random combinatorial peptide library.

Authors: K S Lam; S Wade; F Abdul-Latif; M Lebl
Journal: J Immunol Methods Date: 1995-03-27 Impact factor: 2.303

Review 7. One-bead-one-structure combinatorial libraries.

Authors: M Lebl; V Krchnák; N F Sepetov; B Seligmann; P Strop; S Felder; K S Lam
Journal: Biopolymers Date: 1995 Impact factor: 2.505

8. Multiple release of equimolar amounts of peptides from a polymeric carrier using orthogonal linkage-cleavage chemistry.

Authors: M Lebl; M Pátek; P Kocis; V Krchnák; V J Hruby; S E Salmon; K S Lam
Journal: Int J Pept Protein Res Date: 1993-02

Review 9. Applications of combinatorial technologies to drug discovery. 1. Background and peptide combinatorial libraries.

Authors: M A Gallop; R W Barrett; W J Dower; S P Fodor; E M Gordon
Journal: J Med Chem Date: 1994-04-29 Impact factor: 7.446

10. Discovery of nanomolar ligands for 7-transmembrane G-protein-coupled receptors from a diverse N-(substituted)glycine peptoid library.

Authors: R N Zuckermann; E J Martin; D C Spellmeyer; G B Stauber; K R Shoemaker; J M Kerr; G M Figliozzi; D A Goff; M A Siani; R J Simon
Journal: J Med Chem Date: 1994-08-19 Impact factor: 7.446

2 in total

1. Limitations of the coupling of amino acid mixtures for the preparation of equimolar peptide libraries.

Authors: J A Boutin; I Gesson; J M Henlin; S Bertin; P H Lambert; J P Volland; J L Fauchère
Journal: Mol Divers Date: 1997 Impact factor: 2.943

2. Selection of a histidine-containing inhibitor of gelatinases through deconvolution of combinatorial tetrapeptide libraries.

Authors: G Ferry; J A Boutin; G Atassi; J L Fauchère; G C Tucker
Journal: Mol Divers Date: 1997 Impact factor: 2.943

2 in total