Literature DB >> 7729259

Postischemic intestinal motility in rat is inversely correlated to length of ischemia. An in vivo animal model.

R Udassin1, D Eimerl, J Schiffman, Y Haskel.   

Abstract

An inverse correlation between postischemic gastrointestinal motility and the length of intestinal ischemia was found in an animal model. Intestinal ischemia was caused without concurrent laparotomy and for a predetermined time period (ischemia time) by pulling on an external nylon thread that was threaded through a double-lumen catheter. This catheter was passed into the abdominal cavity to encircle the superior mesenteric artery. Gastrointestinal motility was determined by the introduction of a color-marked meal into the animal's stomach and the measurement of the proportionate length of the small bowel filled with it (transit index). This simple and reliable animal model can also be used for the evaluation of techniques and pharmacological manipulations aimed at modulation of the effects of intestinal ischemia on intestinal motility and its consequences.

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Year:  1995        PMID: 7729259     DOI: 10.1007/bf02064193

Source DB:  PubMed          Journal:  Dig Dis Sci        ISSN: 0163-2116            Impact factor:   3.199


  12 in total

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Journal:  Gastroenterology       Date:  1975-06       Impact factor: 22.682

Review 2.  Bacterial translocation from the gastrointestinal tract.

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Journal:  J Pediatr Surg       Date:  1993-03       Impact factor: 2.545

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Authors:  R Udassin; A Vromen; Y Haskel
Journal:  J Surg Res       Date:  1994-03       Impact factor: 2.192

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  11 in total

1.  Structural and neuronal changes in rat ileum after ischemia with reperfusion.

Authors:  Lille-Mor Lindeström; Eva Ekblad
Journal:  Dig Dis Sci       Date:  2004-08       Impact factor: 3.199

2.  Apoptosis of interstitial cells of Cajal, smooth muscle cells, and enteric neurons induced by intestinal ischemia and reperfusion injury in adult guinea pigs.

Authors:  Feng Mei; Sheng Guo; Yang-tao He; Jiang Zhu; De-shan Zhou; Jian-qin Niu; Han-zhi Wang; Yan-ping Tian
Journal:  Virchows Arch       Date:  2009-02-12       Impact factor: 4.064

3.  Protective effect of proteinase-activated receptor 2 activation on motility impairment and tissue damage induced by intestinal ischemia/reperfusion in rodents.

Authors:  Fiore Cattaruzza; Nicolas Cenac; Elisabetta Barocelli; Mariannina Impicciatore; Eric Hyun; Nathalie Vergnolle; Catia Sternini
Journal:  Am J Pathol       Date:  2006-07       Impact factor: 4.307

4.  Altered responsiveness of the guinea-pig isolated ileum to smooth muscle stimulants and to electrical stimulation after in situ ischemia.

Authors:  Rodolfo Rodriguez; Rosa Ventura-Martinez; Jacinto Santiago-Mejia; Maria R Avila-Costa; Teresa I Fortoul
Journal:  Br J Pharmacol       Date:  2006-02       Impact factor: 8.739

5.  Intestinal motility during hypoxia and reoxygenation in vitro.

Authors:  K Bielefeldt; J L Conklin
Journal:  Dig Dis Sci       Date:  1997-05       Impact factor: 3.199

6.  Endothelin-1 is a candidate mediating intestinal dysmotility in patients with acute pancreatitis.

Authors:  C Y Chen; C L Lu; F Y Chang; R H Lu; W W Ng; S D Lee
Journal:  Dig Dis Sci       Date:  1999-05       Impact factor: 3.199

7.  Febuxostat improves the local and remote organ changes induced by intestinal ischemia/reperfusion in rats.

Authors:  Amani Nabil Shafik
Journal:  Dig Dis Sci       Date:  2012-09-26       Impact factor: 3.199

8.  Protective effects of terminal ileostomy against bacterial translocation in a rat model of intestinal ischemia/reperfusion injury.

Authors:  Zhi-Liang Lin; Wen-Kui Yu; Shan-Jun Tan; Kai-Peng Duan; Yi Dong; Xiao-Wu Bai; Lin Xu; Ning Li
Journal:  World J Gastroenterol       Date:  2014-12-21       Impact factor: 5.742

9.  Tempol reduces bacterial translocation after ischemia/reperfusion injury in a rat model of superior mesenteric artery occlusion.

Authors:  Ibrahim Berber; Cagatay Aydin; Nural Cevahir; Cigdem Yenisey; Gulistan Gumrukcu; Goksel Kocbil; Gurkan Tellioglu; Koray Tekin
Journal:  Surg Today       Date:  2009-04-30       Impact factor: 2.549

10.  Short-term intestinal ischemia-reperfusion alters intestinal motility that can be preserved by xanthine oxidase inhibition.

Authors:  Gülce Hakgüder; Feza M Akgür; Oğuz Ateş; Mustafa Olguner; Tanju Aktuğ; Erdener Ozer
Journal:  Dig Dis Sci       Date:  2002-06       Impact factor: 3.199

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