Literature DB >> 7728908

The formation of peroxynitrite in vivo from nitric oxide and superoxide.

G L Squadrito1, W A Pryor.   

Abstract

Peroxynitrite is predicted to be formed in vivo from the reaction of nitric oxide and superoxide. Nitric oxide at concentrations as low as 3 nM is expected to compete efficiently for superoxide near the surface of endothelial cells, based on competition kinetics.

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Year:  1995        PMID: 7728908     DOI: 10.1016/0009-2797(94)03591-u

Source DB:  PubMed          Journal:  Chem Biol Interact        ISSN: 0009-2797            Impact factor:   5.192


  36 in total

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Review 9.  Role of nitroso radicals as drug targets in circulatory shock.

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10.  Peroxynitrite decreases arrhythmias induced by ischaemia reperfusion in anaesthetized dogs, without involving mitochondrial KATP channels.

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