BACKGROUND: Tunneled venous access devices (VADs) are often essential in the care of patients with advanced malignancies, but they carry an uncertain risk of thrombosis. METHODS: To determine the incidence of venoocclusion related to silicone VADs in a population of adult oncology patients, we prospectively studied 50 individuals with upper extremity venograms approximately 6 weeks after their VADs had been implanted. Twenty-one of these patients were reevaluated with venograms approximately 12 weeks after catheterization. In addition, venograms were performed on a separate group of 24 patients who needed catheterization of axillary-subclavian veins that had been catheterized in the past. RESULTS: The 6-week venograms in the prospective study showed partial venous obstruction in 15 patients (30%), whereas three (6%) had developed symptomatic total venoocclusion by this time. The 12-week venograms showed two additional complete occlusions. Venograms of 30 previously catheterized veins showed complete venoocclusion in nine (30%), although only two had a history of thrombosis. CONCLUSIONS: Our observations indicate that VADs frequently cause partial venoocclusion within the first 6 weeks of catheterization and that permanent venous damage from VADs is common, even without a history of VAD-related thrombosis.
BACKGROUND: Tunneled venous access devices (VADs) are often essential in the care of patients with advanced malignancies, but they carry an uncertain risk of thrombosis. METHODS: To determine the incidence of venoocclusion related to silicone VADs in a population of adult oncology patients, we prospectively studied 50 individuals with upper extremity venograms approximately 6 weeks after their VADs had been implanted. Twenty-one of these patients were reevaluated with venograms approximately 12 weeks after catheterization. In addition, venograms were performed on a separate group of 24 patients who needed catheterization of axillary-subclavian veins that had been catheterized in the past. RESULTS: The 6-week venograms in the prospective study showed partial venous obstruction in 15 patients (30%), whereas three (6%) had developed symptomatic total venoocclusion by this time. The 12-week venograms showed two additional complete occlusions. Venograms of 30 previously catheterized veins showed complete venoocclusion in nine (30%), although only two had a history of thrombosis. CONCLUSIONS: Our observations indicate that VADs frequently cause partial venoocclusion within the first 6 weeks of catheterization and that permanent venous damage from VADs is common, even without a history of VAD-related thrombosis.
Authors: W D Haire; R P Lieberman; J Edney; W P Vaughan; A Kessinger; J O Armitage; J C Goldsmith Journal: Cancer Date: 1990-09-01 Impact factor: 6.860
Authors: F Bozzetti; D Scarpa; G Terno; A Scotti; M Ammatuna; M G Bonalumi; E Ceglia Journal: JPEN J Parenter Enteral Nutr Date: 1983 Nov-Dec Impact factor: 4.016
Authors: Moritz Wildgruber; Sebastian Borgmeyer; Bernhard Haller; Heike Jansen; Jochen Gaa; Marion Kiechle; Reinhard Meier; Johannes Ettl; Hermann Berger Journal: Eur Radiol Date: 2014-09-20 Impact factor: 5.315
Authors: Jo Caers; Christel Fontaine; Vincent Vinh-Hung; Johan De Mey; Gerrit Ponnet; Chris Oost; Jan Lamote; Jacques De Greve; Benjamin Van Camp; Patrick Lacor Journal: Support Care Cancer Date: 2004-11-05 Impact factor: 3.603