Literature DB >> 7721637

Decreased sexual capacity after external radiation therapy for prostate cancer impairs quality of life.

A R Helgason1, M Fredrikson, J Adolfsson, G Steineck.   

Abstract

PURPOSE: The aim of this study was to assess to what extent patients treated with radiation therapy for prostate cancer experience change in sexual functioning and to what extent this effects quality of life. METHODS AND MATERIALS: Information was provided by 53 men treated with radiation therapy for localized prostate cancer. Assessment was made with the "Radiumhemmets Scale of Sexual Functioning," which measures sexual desire, erectile capacity, orgasm, and to what extent a decrease in any of these aspects of sexual functioning affects quality of life. Function before treatment was assessed retrospectively.
RESULTS: Sexual desire diminished among 77% after treatment. The erection stiffness decreased in 77%. Before external radiation therapy, 66% had an erection usually sufficient for intercourse. Half of the men lost this ability after treatment. Of those retaining orgasm after treatment, 47% reported a decreased orgasmic pleasure and 91% a reduced ejaculation volume. Of all men, 50% reported that quality of life had decreased much or very much due to a decline in the erectile capacity following external radiation therapy.
CONCLUSION: The results of the present study indicate that external radiation therapy for prostate cancer is associated with a reduction in sexual desire, erectile capacity, and organism functions. In a majority of patients this reduces quality of life. Previously, we may have underestimated the importance an intact sexual function has for the quality of life in this patient category of elderly men.

Entities:  

Mesh:

Year:  1995        PMID: 7721637     DOI: 10.1016/0360-3016(95)00542-7

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN: 0360-3016            Impact factor:   7.038


  17 in total

Review 1.  Prostatic irradiation-induced sexual dysfunction: a review and multidisciplinary guide to management in the radical radiotherapy era (Part I defining the organ at risk for sexual toxicities).

Authors:  Marigdalia K Ramirez-Fort; Marc J Rogers; Roberto Santiago; Sean S Mahase; Melissa Mendez; Yi Zheng; Xiang Kong; James A Kashanian; M Junaid Niaz; Shearwood McClelland; Xiaodong Wu; Neil H Bander; Peter Schlegel; John P Mulhall; Christopher S Lange
Journal:  Rep Pract Oncol Radiother       Date:  2020-03-19

Review 2.  Psychological Impacts of Male Sexual Dysfunction in Pelvic Cancer Survivorship.

Authors:  David K Twitchell; Daniela A Wittmann; James M Hotaling; Alexander W Pastuszak
Journal:  Sex Med Rev       Date:  2019-03-26

3.  Assessing quality of life in men with clinically localized prostate cancer: development of a new instrument for use in multiple settings.

Authors:  R B Giesler; B J Miles; M E Cowen; M W Kattan
Journal:  Qual Life Res       Date:  2000       Impact factor: 4.147

4.  The effect of erectile dysfunction on quality of life following treatment for localized prostate cancer.

Authors:  D F Penson
Journal:  Rev Urol       Date:  2001

5.  Health-related quality of life in men with erectile dysfunction.

Authors:  M S Litwin; R J Nied; N Dhanani
Journal:  J Gen Intern Med       Date:  1998-03       Impact factor: 5.128

6.  Sexuality after treatment for early prostate cancer: exploring the meanings of "erectile dysfunction".

Authors:  B G Bokhour; J A Clark; T S Inui; R A Silliman; J A Talcott
Journal:  J Gen Intern Med       Date:  2001-10       Impact factor: 5.128

Review 7.  Erectile dysfunction following radiotherapy and brachytherapy for prostate cancer: pathophysiology, prevention and treatment.

Authors:  Cem Akbal; Ilker Tinay; Ferruh Simşek; Levent N Turkeri
Journal:  Int Urol Nephrol       Date:  2008       Impact factor: 2.370

8.  A systematic review of the correlates and management of nonpremature ejaculatory dysfunction in heterosexual men.

Authors:  Raouf Seyam
Journal:  Ther Adv Urol       Date:  2013-10

9.  Proxy assessment of health-related quality of life in african american and white respondents with prostate cancer: perspective matters.

Authors:  A Simon Pickard; Hsiang-Wen Lin; Sara J Knight; Sara L Knight; Roohollah Sharifi; Zhigang Wu; Shih-Ying Hung; Whitney P Witt; Chih-Hung Chang; Charles L Bennett
Journal:  Med Care       Date:  2009-02       Impact factor: 2.983

10.  Sexual rehabilitation after localized prostate cancer: current interventions and future directions.

Authors:  David M Latini; Stacey L Hart; David W Coon; Sara J Knight
Journal:  Cancer J       Date:  2009 Jan-Feb       Impact factor: 3.360

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.