Literature DB >> 7715819

Identification of interleukin-6 (IL-6)-expressing neurons in the cerebellum and hippocampus of normal adult rats.

R A Gadient1, U Otten.   

Abstract

The cellular source of interleukin-6 (IL-6) in brain has not been identified. Using a sensitive, non-radioactive in situ hybridization technique, the cellular localization of IL-6 mRNA in different areas of the rat brain was analysed. Intense staining for IL-6 mRNA was found in Purkinje cells and hippocampal neurons. Our data support an essential role of IL-6 for cerebellar and hippocampal neuron differentiation and function.

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Year:  1994        PMID： 7715819     DOI： 10.1016/0304-3940(94)90807-9

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  37 in total

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